Clinical characteristics of patients with migraine accompanied by tremor. / åå¤´ç—›ä¼´å‘éœ‡é¢¤æ‚£è€ çš„ä¸´åºŠç‰¹å¾.

OBJECTIVES: Migraine and tremor share some genetic mutation sites, and clinical studies have also confirmed their correlation. This study aims to explore the clinical and electrophysiological characteristics of migraine patients with concomitant tremor, and to analyze the relevant influential factors of tremor occurrence. METHODS: We retrospectively analyzed the clinical data of 217 migraine patients who visited the Third Affiliated Hospital of Qiqihar Medical University from June 2022 to October 2023. The Clinical Rating Scale for Tremor (CRST), Numerical Rating Scale (NRS), Generalized Anxiety Disorder-7 (GAD-7), and Patient Health Questionnaire-9 (PHQ-9) were respectively used to assess the tremor symptoms, degree of headache, anxiety, and depression of patients. All patients underwent routine head MR scanning and electromyography examination, and were divided into a migraine with tremor group and a migraine without tremor group based on the electromyogram examination. RESULTS: The migraine with tremor group and the migraine without tremor group were included 52 patients (23.96%) and 165 patients (76.04%), respectively. Compared with the migraine without tremor group, the migraine with tremor group had a longer course and duration of headache, higher frequency of headache attacks, higher NRS score, GAD-7 score, and PHQ-9 score, and fewer weekly physical exercises. The differences were statistically significant (all P<0.05). There were no statistically significant differences in the presence or absence of prodromal headache and white matter hyperintensities (WMHs) between the 2 groups (both P>0.05). The evaluation results of the CRST showed that out of 217 migraine patients, 39 patients (17.97%) were accompanied by tremors. The electromyographic results showed that all 52 migraine patients with tremors had upper limb tremors, including 28 migraine patients with postural tremors and 24 migraine patients with static tremors. Compared with the migraine patients with static tremors, the migraine patients with postural tremors had lower average frequency, peak frequency, and headache onset frequency (all P<0.05). Multiple linear regression analysis showed that frequency of physical exercise, duration of illness, frequency of headache attacks, NRS score, GAD-7 score, and PHQ-9 score were risk factors for migraine patients with concomitant tremors (all P<0.05). CONCLUSIONS: Patients with migraine mainly experience upper limb postural tremors. Reduced physical exercise, long course of disease, long duration of headache, frequent headache attacks, severe headache, anxiety, and depression are risk factors for migraine patients with concomitant tremors.

The Spectrum of Non-Parkinsonian Tremor: A Registry at a Tertiary Care Teaching Institute.

Background: Tremors other than those associated with Parkinson's disease (non-parkinsonian tremor) are commonly observed in clinical settings. However, their frequency and clinical characteristics have rarely been reported. Objectives: To classify non-parkinsonian tremors based on the consensus statement on the classification of tremors, from the task force of the International Parkinson and Movement Disorder Society published in 2018. Methods: A prospective registry at a tertiary care teaching institute. Results: A total of 475 patients with non-parkinsonian tremors were recruited for the study. 67.57% (n = 321) of our patients were male and a family history of tremor was present in 20.84% (n = 99) of patients. Dystonic tremor (DT) was the most common non-parkinsonian tremor (33.26%). 27.78% of patients fulfilled the new classification criteria for essential tremor, with 13.47% classified as pure ET (ET) and 14.31% exhibiting neurological soft signs, leading to the classification of ET plus (ETP). Patients with ETP had more family history (57.35%) [vs DT (26.48%, p = 0.00004) and ET (10.93%, p = 0.00003], longer duration of disease [mean ± standard deviation (SD) = 9.53 ± 8.64 years] [vs DT (5.60 ± 5.93, p = 0.0003) and ET (6.38 ± 5.97, p = 0.01) years], and more severe tremor as measured by the essential tremor rating assessment scale total score [mean ± SD = 27.42 ± 11.70] [vs DT (23.50 ± 8.62, p = 0.007) and ET (22.12 ± 8.19, p = 0.007)] compared with patients with DT and ET. Conclusions: DT was the most common cause of non-parkinsonian tremor in our registry followed by essential tremor syndrome. ETP was more common than ET.

Evaluación de la incidencia de temblores en la sala de recuperación postanestésica / Evaluation of the incidence trembling in the recovery room postanesthtic / Avaliação da incidência de tremores na sala de recuperação posanestesica

Los temblores son una complicación frecuente, desagradable y que pueden relacionarse a un aumento de la morbilidad del período postoperatorio. El propósito de este estudio fue determinar la frecuencia de presentación de temblores en el postoperatorio inmediato. Pacientes y métodos: Se estudiaron 119 pacientes adultos, operados de coordinación una vez que ingresaron a la Sala de Recuperación Postanestésica (SRPA). Se consignó la presencia y severidad (grado I a IV) de temblores al ingreso y luego cada 15 minutos. Se trataron mediante medidas de recalentamiento externo, ondansetrón y meperidina, de manera escalonada cada 15 minutos. Resultados: hubo 24 (21.2 %) pacientes con temblores postoperatorios, 17/24 (71%) asociados a hipotermia. En 8 (33,3%) pacientes el temblor fue grado I, en 2 (8,3%) fueron grado II, y en 14 (58,3%) fueron grado III. En todos los casos cedieron con el tratamiento pautado y no más allá de los 45 minutos. Conclusiones: Los temblores fueron una complicación frecuente en la SRPA, asociados a hipotermia en la mayor parte de los casos, pero de duración limitada, y fácilmente tratables.

Trembling are frequent, unpleasant complication and can relate to increased morbidity postoperative period. The purpose of this study was to determine the frequency of occurrence of earthquakes in the immediate postoperative period. Patients and Methods: 119 adult patients operated coordination once entered the recovery room (PACU) were studied. the presence and severity (grade I to IV) of tremors at admission and then every 15 minutes was recorded. They were treated by external measures, ondansetron and meperidine overheating, staggered every 15 minutes. Avaliação da incidência de tremores na sala de recuperação posanestesica.

Tremores é uma complicação freqüente, desagradável e que pode relacionar-se a um aumento da morbilidade do período posoperatorio. O propósito deste estudo foi determinar a freqüência de manifestação de tremores no posoperatorio imediato. Pacientes e métodos: Estudaram-se 119 pacientes adultos, de cirurgias eletivas que chegaram à Sala de Recuperação Posanestesica (SRPA). Registraram-se a presença e severidade (grado I a IV) de tremores ao ingresso e cada 15 minutos. O tratamento foi: medidas de aquecimento externo, ondansetron e meperidina de maneira alternativa cada 15 minutos. Resultados. Teve 24 (21.2%) de pacientes com tremores posoperatorio, 17/24 (71%) associados à hipotermia. Em 8 (33,3%) pacientes o tremor foi grado I, em 2 (8,3%) foi grado II, em 14 (58,3%) grado III. Todos os casos acalmaram com o tratamento pautado nos primeiros 45 minutos. Conclusões. Os tremores foram uma complicação freqüente em SRPA, associado à hipotermia na maioria dos casos, com duração limitada e de fácil tratamento.

Estudio piloto de la prevalencia de las principales enfermedades neurológicas en el Uruguay / The prevalence of leading neurologic diseases in Uruguay: a pilot study

Se proyectó un estudio para estimar la prevalencia de las principales enfermedades neurológicas en el Uruguay. El estudio piloto fue llevado a cabo en Migues, población semirural al noreste de Montevideo. Se trata de un estudio epidemiológico transversal en dos fases: en la primera de ellas se realiza un cuestionario puerta a puerta, en la segunda se examina a las personas-posibles portadoras de las enfermedades en estudio. Se puso a prueba el diseño y la metodología y se estudió la sensibilidad y especificidad de los instrumentos utilizados. Se encuestaron un total de 682 hogares que corresponden a los 1975 habitantes de la localidad. Se obtuvieron las siguientes tasas de equivalencia puntuales: epilepsia 9,1 por 1000, convulsiones febriles 7,2 por 1000, accidentes vasculares encefálicos 7,6 por 1000, accidentes isquémicos transitorios 4,6 por 1000, enfermedad de Parkinson 4,0 por 1000, temblor esencial 8,6 por 1000, síndromes demenciales 10,6 por 1000. Se concluye a la factibilidad del estudio, habiendose obtenido cifras de sensibilidad y especificidad variables para cada área, pero todas ellas dentro de los parámetros aceptables. Se discuten los errores cometidos así como se proponen soluciones para corregir los mismos en vistas al estudio definitivo que proyecta realizarse con una población de mayor talla

Marcadores semiológicos en el diagnóstico diferencial del temblor parkinsoniano y esencial / Physical markers in the differential diagnosis of parkinsonian and essential tremor

Con el objeto de determinar los signos de mayor utilidad para el diagnóstico diferencial del temblor parkinsoniano y escencial se estudiaron 128 pacientes (64 hombres de 64,4 + ó - 14,1 años y 64 mujeres de 67,9 + ó- 7,7 años). Se tomaron en cuenta 16 parámetros semiológicos especialmente definidos, que fueron evaluados estadísticamente y relacionados con los diagnósticos preestablecidos. Los parámetros temblor de actitud e intencional, marcha de pequeños pasos, reflejo palmomentoniano y antecedentes familiares no se agruparon en forma significativa. Los parámetros actitud en flexión, temblor de reposo, adiadococinesia, reducción de balanceo, rueda dentada en codo, muñeca y miembros inferiores, reflejos de hociqueo y nasopalpebral patológico, trastornos vegetativos y amimia se agruparon significativamente en 64 pacientes (p <0,05) en los cuales el diagnóstico presuntivo fue temblor parkinsoniano. Se concluye que para el diagnóstico diferencial del temblor parkinsoniano y escencial son de mayor utilidad la presencia o ausencia de algunos signos asociados (marcadores) que las características semiológicas del temblor mismo