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1.
Univ. salud ; 27(1): 1-10, enero-abril 2025.
Artigo em Espanhol | LILACS | ID: biblio-1555921

RESUMO

Introducción: La calidad de vida relacionada con la salud (CVRS) y los estados de ánimo son indicadores cruciales del bienestar en adolescentes, pero su relación con estudiantes de Antioquia, Colombia, no ha sido ampliamente estudiada. Objetivo: Determinar la CVRS y los estados de ánimo en escolares de Antioquia-Colombia. Materiales y métodos: Estudio transversal con 1957 escolares de 9 a 20 años. Se aplicaron mediciones de CVRS, ansiedad, depresión, hostilidad y alegría, actividad física, comportamiento sedentario, apoyo social de padres y nivel socioeconómico. Resultados: La calidad de vida alta (CVA) es más elevada en hombres, personas con alegría, estudiantes con apoyo de padres, activos físicamente y personas de nivel socioeconómico alto y medio. AL aumentar un año de edad, disminuye en un 15 % la CVA, y al aumentar la depresión, la ansiedad y el comportamiento sedentario disminuye la CVA. Además, los niveles de depresión y ansiedad son mayores en mujeres, estudiantes mayores, sin apoyo de los padres y personas sedentarias. Conclusiones: La CVRS se asocia con estados de ánimo, actividad física, comportamiento sedentario y apoyo de los padres; mientras que los estados de ánimo se asocian con el sexo, el apoyo de los padres, la CVS y el sedentarismo.


Introduction: Even though health-related quality of life (HRQL) and mood states are key indicators of the well-being of adolescents, their relationship has not been analyzed in students from Antioquia, Colombia. Objective: To determine HRQL and mood states in schoolchildren from Antioquia. Materials and methods: A cross-sectional study was conducted on 1,957 schoolchildren and adolescents aged between 9 and 20 years. Measurements of HRQL, anxiety, depression, hostility and happiness, physical activity, sedentary behavior, parental social support, and socioeconomic status were applied. Results: A high quality of life (HQL) was observed more frequently in male participants, students with parental support, physically active, and those belonging to medium and high socioeconomic status. HQL decreased 15% as their age increased by one year. Also, HQL was reduced when depression, anxiety, and sedentary behavior increased. Furthermore, depression and anxiety levels were higher in women, older students, as well as in those without parental control and with sedentary behavior. Conclusions: HRQL is associated with mood states, physical activity, sedentary behavior, and parental support. In contrast, mood states are related to gender, parental support, HQL, and sedentary lifestyle.


Introdução: A qualidade de vida relacionada à saúde (CVRS) e os estados de humor são indicadores cruciais de bem-estar em adolescentes, mas sua relação com estudantes de Antioquia, Colômbia, não foi amplamente estudada. Objetivo: Determinar a CVRS e os estados de humor em escolares de Antioquia-Colômbia. Materiais e métodos: Estudo transversal com 1.957 escolares de 9 a 20 anos. Foram aplicadas medidas de QVRS, ansiedade, depressão, hostilidade e felicidade, atividade física, comportamento sedentário, apoio social dos pais e nível socioeconômico. Resultados: A alta qualidade de vida (CVA) é maior em homens, pessoas com alegria, estudantes com apoio parental, fisicamente ativos e pessoas de nível socioeconômico alto e médio. À medida que a idade aumenta em um ano, diminui em 15% o CVA, e ao aumentar a depressão, a ansiedade e o comportamento sedentário aumentam, o CVA diminui. Além disso, os níveis de depressão e ansiedade são mais elevados nas mulheres, nos estudantes mais velhos, sem apoio dos pais e nas pessoas sedentárias. Conclusões: A QVRS está associada a estados de humor, atividade física, comportamento sedentário e apoio parental; enquanto os estados de humor estão associados ao sexo, apoio parental, CVS e estilo de vida sedentário.


Assuntos
Humanos , Masculino , Feminino , Criança , Adolescente , Adulto Jovem , Saúde , Emoções , Felicidade , Hostilidade
2.
J Environ Sci (China) ; 148: 691-701, 2025 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-39095201

RESUMO

Personal care products (PCPs) are a class of emerging pollutants that have attracted public concern owing to their harmful effects on humans and the environment. Biomonitoring data is valuable for insight the levels of PCPs in the human body and can be crucial for identifying potential health hazards. To gain a better understanding of timely exposure profiles and health risk of reproductive-age population to PCPs, we determined six parabens, six benzophenone-type ultraviolet filters, and three disinfectants in 256 urine samples collected from young adults aged 18-44 years in Beijing, China. The urinary levels of benzophenone-3 (BP-3) and 4-hydroxybenzophenone (4-OHBP) were significantly higher in summer compared to winter, suggesting these compounds have different seasonal usage patterns. Moreover, the total concentration of 15 PCPs in female was 430 ng/mL, approximately two times higher than that in male. P­chloro-m-xylenol (PCMX), as a new type of antibacterial agent, has the greatest level among all target analytes, indicating the increasingly use of this antibacterial alternative recently. Five potential influencing factors that lead to the elevated exposure level of PCPs were identified. Over 19% of the target population had a high hazard index value (greater than 1) which was attributed to exposure to propyl paraben (PrP), benzophenone-1 (BP-1), BP-3 and PCMX, indicating that PCPs may pose a relatively high exposure risk at environmental levels that should be a cause for concern.


Assuntos
Cosméticos , Exposição Ambiental , Humanos , Adulto , Adulto Jovem , Medição de Risco , Feminino , Masculino , Adolescente , Cosméticos/análise , Exposição Ambiental/estatística & dados numéricos , Exposição Ambiental/análise , Pequim , Poluentes Ambientais/análise , Benzofenonas/urina , Monitoramento Ambiental
3.
Food Chem ; 462: 140969, 2025 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-39197245

RESUMO

Alcoholic beverages flavour is complex and unique with different alcohol content, and the application of flavour perception could improve the objectivity of flavour evaluation. This study utilized electroencephalogram (EEG) to assess brain reactions to alcohol percentages (5 %-53 %) and Baijiu's complex flavours. The findings demonstrate the brain's proficiency in discerning between alcohol concentrations, evidenced by increasing physiological signal strength in tandem with alcohol content. When contrasted with alcohol solutions of equivalent concentrations, Baijiu prompts a more significant activation of brain signals, underscoring EEG's capability to detect subtleties due to flavour complexity. Additionally, the study reveals notable correlations, with δ and α wave intensities escalating in response to alcohol stimulation, coupled with substantial activation in the frontal, parietal, and right temporal regions. These insights verify the efficacy of EEG in charting the brain's engagement with alcoholic flavours, setting the stage for more detailed exploration into the neural encoding of these sensory experiences.


Assuntos
Bebidas Alcoólicas , Encéfalo , Eletroencefalografia , Etanol , Humanos , Encéfalo/efeitos dos fármacos , Encéfalo/fisiologia , Encéfalo/metabolismo , Adulto , Bebidas Alcoólicas/análise , Masculino , Adulto Jovem , Feminino , Etanol/análise , Paladar , Aromatizantes/química , Percepção Gustatória
4.
Clin Chim Acta ; 564: 119938, 2025 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-39181293

RESUMO

OBJECTIVE: Delta bilirubin (albumin-covalently bound bilirubin) may provide important clinical utility in identifying impaired hepatic excretion of conjugated bilirubin, but it cannot be measured in real-time for diagnostic purposes in clinical laboratories. METHODS: A total of 210 samples were collected, and their delta bilirubin levels were measured four times using high-performance liquid chromatography. Data collected included age, sex, diagnosis code, delta bilirubin, total bilirubin, direct bilirubin, total protein, albumin, globulin, aspartate aminotransferase, alanine transaminase, alkaline phosphatase, gamma-glutamyl transferase, lactate dehydrogenase, hemoglobin, serum hemolysis value, hemolysis index, icterus value (Iv), icterus index (Ii), lipemia value (Lv), and lipemia index. To conduct feature selection and identify the optimal combination of variables, linear regression machine learning was performed 1,000 times. RESULTS: The selected variables were total bilirubin, direct bilirubin, total protein, albumin, hemoglobin, Iv, Ii, and Lv. The best predictive performance for high delta bilirubin concentrations was achieved with the combination of albumin-direct bilirubin-hemoglobin-Iv-Lv. The final equation composed of these variables was as follows: delta bilirubin = 0.35 × Iv + 0.05 × Lv - 0.23 × direct bilirubin - 0.05 × hemoglobin - 0.04 × albumin + 0.10. CONCLUSION: The equation established in this study is practical and can be easily applied in real-time in clinical laboratories.


Assuntos
Bilirrubina , Aprendizado de Máquina , Bilirrubina/sangue , Humanos , Feminino , Masculino , Pessoa de Meia-Idade , Adulto , Idoso , Adolescente , Adulto Jovem , Criança , Idoso de 80 Anos ou mais , Cromatografia Líquida de Alta Pressão , Pré-Escolar , Lactente
5.
Asian J Endosc Surg ; 18(1): e13391, 2025.
Artigo em Inglês | MEDLINE | ID: mdl-39406382

RESUMO

BACKGROUND AND OBJECTIVE: Hydatid cyst is a benign parasitic disease that is usually asymptomatic and is discovered incidentally. The gold standard for the treatment of this disease is surgery. Recently, a laparoscopic approach has been used to remove hydatid cysts. We decided to compare this new technique with an open conventional method. MATERIALS AND METHODS: Patients-This retrospective analytical study was conducted on patients with hepatic hydatid cysts who underwent surgery in Kashan during 2013-2020. A total of 58 patients were included in this study, 18 of whom underwent laparoscopic surgery and 40 underwent open surgery. The comparison of the two groups was performed using chi-square and Fisher's exact tests. RESULTS: The average duration of surgery in the laparoscopic and open surgery groups was 135 and 151.6 min, respectively, which was not statistically significant (p-value = .179). There was no significant difference in terms of the need for blood transfusion, conversion of laparoscopic surgery to open surgery, anaphylactic shock, infection, and death between the two groups (p > .05). However, the laparoscopic surgery group had a significantly shorter hospital stay compared with the open surgery group (p-value < .001), and more favorite patients. CONCLUSION: Considering the lack of significant difference between the two surgical methods and the reduction in the duration of surgery by a laparoscopic approach, the reduction in hospital stay of patients, and consequently the reduction in the cost of patients, it is expected that this method is a more suitable method compared with open surgery.


Assuntos
Equinococose Hepática , Laparoscopia , Complicações Pós-Operatórias , Humanos , Laparoscopia/efeitos adversos , Estudos Retrospectivos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Complicações Pós-Operatórias/epidemiologia , Equinococose Hepática/cirurgia , Tempo de Internação/estatística & dados numéricos , Duração da Cirurgia , Idoso , Adulto Jovem
6.
Food Chem ; 462: 140704, 2025 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-39226642

RESUMO

Clove (Syzygium aromaticum) is one of the most commonly used spices in stewed beef to enrich and improve its aroma during the stewing process. Gas chromatography ion mobility spectroscopy (GC-IMS), Q Exactive GC-Orbitrap-MS-O (QE-GC-MS/O), combined with sensory evaluation were employed to analyze the flavor endowment of aroma-active compounds in cloves to stewed beef. A total of 173 volatiles were identified in the clove powder (CP), stewed beef with clove (SBC), and stewed beef with salt (SBS), of which 21 volatiles were considered as aroma-active compounds. The concept of flavor endowment of aroma-active compounds in cloves was defined innovatively, and the endowment rate values (ERVs) of stewed beef were calculated. Nine aroma-active compounds in cloves were found to have a flavor endowment effect on stewed beef, while the terpenoids exhibited high ERVs. Despite the low ERV of eugenol, it still significantly impacted the aroma profile of SBC due to its high odor activity value (OAV) and flavor dilution (FD) factor. These volatiles offered mainly the clove, herbal, anise, and floral odor to stewed beef, which was also confirmed by sensory evaluation. These findings indicated that the terpenoids, phenolics and ethers in cloves had a significant influence on the overall aroma of stewed beef through the flavor endowment, which contributed to the precise use of cloves and improved the aroma of stewed beef.


Assuntos
Aromatizantes , Cromatografia Gasosa-Espectrometria de Massas , Odorantes , Syzygium , Paladar , Compostos Orgânicos Voláteis , Syzygium/química , Bovinos , Compostos Orgânicos Voláteis/química , Odorantes/análise , Humanos , Animais , Aromatizantes/química , Adulto , Feminino , Masculino , Especiarias/análise , Culinária , Adulto Jovem , Carne Vermelha/análise
7.
Clin Chim Acta ; 564: 119901, 2025 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-39134218

RESUMO

BACKGROUND: Platelet contains growth factors that enhance tissue repair mechanisms, including epidermal growth factor (EGF), platelet-derived growth factor (PDGF-AA and -AB), and transforming growth factor (TGF)-ß. Autologous platelet-rich plasma (PRP) has been shown to significantly improve the treatment of tendon injuries compared with hyaluronic acid and placebo. The topic of agreement between platelet concentrations and growth factors has been covered in some previous studies, but growth factor levels did not correlate well with platelet concentrations. METHOD: In this study, autologous PRP was prepared by concentrating platelets through a J6-MI centrifuge. The automatic hematology analyzer Sysmex XN-20 was used to analyze the platelet concentration in PRP, and the PRP growth factors were determined by ELISA, including PDGF, transforming growth factor- ß1 (TGF-ß1), and EGF. Statistical analysis was conducted on data from 107 patients who received autologous PRP using Pearson correlation analysis. RESULTS: Pearson correlation analysis revealed PDGF, TGF, and EGF had a strong positive correlation with the platelet concentration of the final PRP product (r = 0.697, p < 0.0001; r = 0.488, p < 0.0001; r = 0.572, p < 0.0001, respectively) CONCLUSIONS: There was a strong positive correlation between the concentration of platelets in the final PRP product and the levels of PDGF-AB, TGF-ß, and EGF. These results suggested straightforward and cost-effective growth factor tests can provide valuable information about platelet content in PRP.


Assuntos
Peptídeos e Proteínas de Sinalização Intercelular , Plasma Rico em Plaquetas , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Peptídeos e Proteínas de Sinalização Intercelular/sangue , Contagem de Plaquetas , Plasma Rico em Plaquetas/metabolismo , Plasma Rico em Plaquetas/química
8.
Clin Chim Acta ; 564: 119943, 2025 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-39191346

RESUMO

BACKGROUND-AIM: Methylmalonic acid (MMA) is currently the best biomarker of functional vitamin B12 deficiency. However, for a correct interpretation of the patient's results it is necessary to know its biological variation (BV). No BV data are available for urine MMA values, as measured by mass spectrometry. Hence, the aim of this study was to estimate the within- and between-person coefficients of variation (CVw, CVg) for MMA in a healthy population, and the associated index of individuality (II), as well as to define quality specifications based on BV and the reference change value (RCV). METHODS: Random urine samples from 34 healthy volunteers were collected over four consecutive weeks. Samples were stored at -80 °C until analysis in a single analytical run. MMA excretion was quantified by tandem liquid chromatography coupled to mass spectrometry (HPLC-MS/MS). Results were normalized to urine creatinine. The coefficients of variation were estimated by CV-ANOVA. Confidence intervals (95 %) were calculated. Quality specifications were defined according to international recommendations. RESULTS: A total of 128 samples were included. The coefficients of variation were CVw = 35.7 % (26.1-45.3) and CVg = 67.7 % (58.3-77.0). The associated II was 0.5 and the RCV was 88.1 %. CONCLUSION: Considering the II obtained, MMA in urine has high individuality, therefore, RCV is better to evaluate serial clinical results. Our results will contribute to a better clinical interpretation of this biomarker and will represent a great aid when defining analytical performance specifications for this magnitude.


Assuntos
Ácido Metilmalônico , Humanos , Ácido Metilmalônico/urina , Masculino , Adulto , Feminino , Espanha , Espectrometria de Massas em Tandem , Pessoa de Meia-Idade , Adulto Jovem , Voluntários Saudáveis , Cromatografia Líquida de Alta Pressão , Biomarcadores/urina
9.
J Appl Res Intellect Disabil ; 38(1): e13311, 2025 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-39448390

RESUMO

BACKGROUND: At least half of children and adults with Down syndrome have a major mental health concern during their life but few studies ask people with Down syndrome directly about their experience. We used a co-research model to explore anxiety, stress, and coping in adults with Down syndrome. METHODS: Our group of researchers and adults with Down syndrome conducted an online survey on mental health for adults with Down syndrome. We analysed quantitative data and thematically grouped coping mechanisms. RESULTS: Sixty adults with Down syndrome completed the survey, mean age was 30 years, and 55% of respondents had some employment. Approximately 80% of respondents reported experiencing stress and 75% reported experiencing anxiety. Employed respondents were more likely to use social coping mechanisms. CONCLUSION: Soliciting responses from adults with Down syndrome about their mental health can provide valuable insights. Mental health is a concern for people with Down syndrome that should be addressed.


Assuntos
Adaptação Psicológica , Ansiedade , Síndrome de Down , Estresse Psicológico , Humanos , Síndrome de Down/psicologia , Adulto , Masculino , Feminino , Ansiedade/psicologia , Estresse Psicológico/psicologia , Adulto Jovem , Pessoa de Meia-Idade , Adolescente
10.
J Appl Res Intellect Disabil ; 38(1): e13315, 2025 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-39448449

RESUMO

BACKGROUND: Individuals with intellectual disabilities are at increased risk of mental health disorders, but may struggle to access appropriate services. While assessment/treatment may need to be adapted, knowledge is limited about what such adaptations may entail. METHOD: During a service development project, the participants (33 professionals, 13 family members) were asked to identify the characteristics/associated factors of individuals with intellectual disabilities and co-occurring mental health disorders. Using thematic analysis, 1103 participant responses were analyzed to identify the needs for adaptation in assessment/treatment. RESULTS: Three core themes were identified: (1) A broader assessment: Gaining an accurate and comprehensive understanding of the individual's history, abilities and difficulties, (2) Adjusting/modifying existing treatment strategies, (3) Ensuring that the individual's day-to-day needs are met. CONCLUSIONS: According to the participants, assessment/treatment of mental health disorder in this population requires more time and broader assessments are necessary. Family/caregiver involvement and cross-service organisation/collaboration represent other important adaptations.


Assuntos
Deficiência Intelectual , Transtornos Mentais , Serviços de Saúde Mental , Pesquisa Qualitativa , Humanos , Deficiência Intelectual/terapia , Adulto , Masculino , Feminino , Transtornos Mentais/terapia , Pessoa de Meia-Idade , Adulto Jovem , Família/psicologia
11.
J Appl Res Intellect Disabil ; 38(1): e13313, 2025 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-39448520

RESUMO

BACKGROUND: Given the current sociopolitical climate, people with intellectual disabilities are spending more time at home. Much housing-related research focuses on informant-completed measures and quantifiable outcomes. By contrast, this article explores the perspectives of adults with intellectual disabilities concerning what they liked or disliked about their homes. METHOD: Data is drawn from 53 semi-structured interviews with people with intellectual disabilities in supported living or residential care in England. RESULTS: Three themes were generated: space and place; people make or break a home; and day-to-day autonomy. These highlight the importance of belonging and the significance of other people in the creation of 'home'. CONCLUSION: If people are to flourish, attention must be paid to aspects of the home that provide comfort, enjoyment, and a sense of belonging. These findings can benefit professionals, family members and people with intellectual disabilities, when considering current or future living arrangements.


Assuntos
Deficiência Intelectual , Humanos , Deficiência Intelectual/psicologia , Adulto , Feminino , Masculino , Pessoa de Meia-Idade , Instituições Residenciais , Pesquisa Qualitativa , Autonomia Pessoal , Inglaterra , Idoso , Adulto Jovem , Moradias Assistidas
12.
J Appl Res Intellect Disabil ; 38(1): e13314, 2025 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-39449059

RESUMO

BACKGROUND: During the COVID-19 pandemic we implemented a partially online music intervention to examine the feasibility, experiences and short-term outcomes on the challenging behaviour and well-being of adults with intellectual disabilities. METHOD: This mixed-methods study included 10 participants with mild or moderate intellectual disabilities who received 16 one-hour individual music sessions in 10 weeks, either face-to-face or online. Data on feasibility and experiences from participants and music workers were collected and analysed using inductive thematic analysis. Challenging behaviour and well-being were measured before and after intervention. RESULTS: Overall experiences were positive and concerned appreciation, positive feelings, musical abilities, attention span, relatedness and personalisation. Online experiences varied, but most participants preferred face-to-face over online sessions. After the intervention, challenging behaviour scores were better than before. CONCLUSIONS: Engaging in a partially online music intervention is feasible for people with intellectual disabilities and seems to improve challenging behaviour. Experiences are discussed and recommendations for future online sessions are provided.


Assuntos
Estudos de Viabilidade , Deficiência Intelectual , Musicoterapia , Comportamento Problema , Humanos , Deficiência Intelectual/reabilitação , Musicoterapia/métodos , Projetos Piloto , Adulto , Masculino , Feminino , Pessoa de Meia-Idade , COVID-19 , Intervenção Baseada em Internet , Adulto Jovem
13.
J Appl Res Intellect Disabil ; 38(1): e13310, 2025 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-39444261

RESUMO

BACKGROUND: Canadian 24-h movement guidelines recommend that adults achieve 150 min per week of moderate-to-vigorous physical activity (MVPA), 7-9 h of sleep per night and spend no more than 8-h per day sedentary to optimise health and wellbeing. METHOD: Using a cross-sectional survey of 131 family caregivers of adults with intellectual and developmental disabilities, we aimed to (a) determine whether adherence to these guidelines predicts mental wellbeing in family caregivers and (b) explore the relationship between movement behaviours of family caregivers and their loved ones. RESULTS: While MVPA was found to weakly predict wellbeing, sleep and sedentary behaviour did not. The movement behaviours of the family caregivers were not closely related to that of their loved ones. CONCLUSIONS: Fostering physical activity is important to promote the wellbeing of adults with intellectual and developmental disabilities, as well as their family caregivers. Opportunities to be active together may be even more beneficial.


Assuntos
Cuidadores , Deficiências do Desenvolvimento , Exercício Físico , Deficiência Intelectual , Saúde Mental , Comportamento Sedentário , Sono , Humanos , Masculino , Cuidadores/psicologia , Feminino , Deficiência Intelectual/enfermagem , Adulto , Deficiências do Desenvolvimento/enfermagem , Pessoa de Meia-Idade , Estudos Transversais , Sono/fisiologia , Idoso , Adulto Jovem , Canadá , Família/psicologia
14.
Med Gas Res ; 15(1): 156-163, 2025 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-39324933

RESUMO

The use of hyperbaric oxygen (HBO 2 ) in the field of traumatic brain injury (TBI) is becoming more widespread and increasing yearly, however there are few prognostic reports on long-term functional efficacy. The aim of this study was to assess the functional prognosis of patients with moderate-to-severe TBI 5-8 years following HBO 2 treatments and to explore the optimal HBO 2 regimen associated with prognosis, using a retrospective study. Clinical data were retrospectively collected as a baseline for patients with moderate-to-severe TBI treated with HBO 2 during inpatient rehabilitation from January 2014 to December 2017. The primary outcome measure was the Disability Rating Scale (DRS) and the secondary outcome measure was the Glasgow Outcome Scale. A total of 133 patients enrolled, with 9 (6.8%) dying, 41 (30.8%) remaining moderately disabled or worse (DRS scores 4-29), 83 (62.4%) remaining partially/mildly disabled or no disability (DRS scores 0-3). Logistic regression analysis revealed that age at injury (odds ratio (OR), 0.96; 95% confidence interval (CI), 0.92-0.99), length of intensive care unit stay (OR, 0.94; 95% CI, 0.88-0.99), and HBO 2 sessions (OR, 0.97; 95% CI, 0.95-0.99) were variables that independently influenced long-term prognosis. Cubic fitting models revealed that 14 and 21.6 sessions of HBO 2 could be effective for moderate and severe TBI, respectively. This study highlighted that HBO 2 in moderate-to-severe TBI may contribute to minimize death and reduce overall disability in the long-term. However, clinicians should be cautious of the potential risk of adverse long-term prognosis from excessive HBO 2 exposure when tailoring individualized HBO 2 regimens for patients with moderate-to-severe TBI. The study was registered on ClinicalTrials.gov (NCT05387018) on March 31, 2022.


Assuntos
Lesões Encefálicas Traumáticas , Oxigenoterapia Hiperbárica , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Lesões Encefálicas Traumáticas/terapia , Prognóstico , Estudos Retrospectivos , Resultado do Tratamento
15.
Artigo em Espanhol | LILACS, BNUY, UY-BNMED | ID: biblio-1568770

RESUMO

La evaluación de la marcha en cinta caminadora puede resultar relevante para la toma de decisiones clínicas. No obstante, factores demográficos como la edad y el IMC pueden alterar la interpretación de los resultados. Nuestro objetivo fue obtener variables espacio- temporales, energéticas y costo de transporte durante la velocidad autoseleccionada en cinta caminadora para una muestra representativa de adultos uruguayos (n=28) y evaluar si diferentes rangos de edades e IMC pueden ser factores a tener en cuenta en pruebas clínicas donde se consideren dichas variables. Participaron 17 hombres y 11 mujeres (39,3 ± 14,8 años, 75,9 ± 12,5 kg, 1,74 ± 0,09 m, IMC 25,2 ± 4,06). Se realizó una reconstrucción 3D del movimiento en forma sincronizada con el consumo energético. Se obtuvieron valores de referencia y luego de agrupar los participantes según su IMC y rango de edad se compararon los datos mediante test de t (p≤0.05). Los resultados revelaron discrepancias significativas en las medidas espacio-temporales y energéticas de los adultos uruguayos al caminar en cinta con respecto a la literatura. La marcha difiere entre adultos jóvenes y de mediana edad en su velocidad autoseleccionada (p=0,03), longitud de zancada (p=0,01), trabajo mecánico externo (<0,001) y recuperación de energía mecánica (0,009), destacando la importancia de considerar la edad en evaluaciones clínicas. El IMC no influyó significativamente en estas variables. Estos hallazgos subrayan la necesidad de ajustar las interpretaciones de las pruebas clínicas de la marcha sobre cinta caminadora en adultos uruguayos de mediana edad (45 a 65 años).


Treadmill gait assessment can be relevant for clinical decision-making. However, demographic factors such as age and BMI may alter result interpretation. Our aim was to obtain spatiotemporal, energetic, and cost of transport variables during self-selected treadmill walking speed for a representative sample of Uruguayan adults (n=28) and to assess if different age ranges and BMI could be factors to consider in clinical tests involving these variables. Seventeen men and eleven women participated (39.3 ± 14.8 years, 75.9 ± 12.5 kg, 1.74 ± 0.09 m, BMI 25.2 ± 4.06). A synchronized 3D motion reconstruction was performed with energy consumption. Reference values were obtained and data were compared using t-tests (p≤0.05), after grouping participants by BMI and age range. Results revealed significant discrepancies in spatiotemporal and energetic measures of Uruguayan adults walking on the treadmill, compared to the literature. Gait differed between young and middle-aged adults in their self-selected speed (p=0.03), stride length (p=0.01), external mechanical work (p<0.001), and mechanical energy recovery (0.009), emphasizing the importance of considering age in clinical evaluations. BMI did not significantly influence these variables. These findings underscore the need to adjust interpretations of treadmill gait clinical tests in middle-aged Uruguayan adults (45 to 65 years).


A avaliação da marcha na esteira pode ser relevante para a tomada de decisões clínicas. No entanto, fatores demográficos como idade e IMC podem alterar a interpretação dos resultados. Nosso objetivo foi obter variáveis espaço-temporais, energéticas e custo de transporte durante a velocidade de caminhada autoselecionada na esteira para uma amostra representativa de adultos uruguaios (n = 28) e avaliar se diferentes faixas etárias e IMC podem ser fatores a serem considerados em testes clínicos que envolvam essas variáveis. Dezessete homens e onze mulheres participaram (39,3 ± 14,8 anos, 75,9 ± 12,5 kg, 1,74 ± 0,09 m, IMC 25,2 ± 4,06). Foi realizada uma reconstrução tridimensional do movimento sincronizada com o consumo de energia. Foram obtidos valores de referência e os dados foram comparados usando testes t (p≤0,05), após agrupar os participantes por IMC e faixa etária. Os resultados revelaram discrepâncias significativas nas medidas espaço-temporais e energéticas dos adultos uruguaios ao caminhar na esteira, em comparação com a literatura. A marcha diferiu entre adultos jovens e de meia-idade em sua velocidade autoselecionada (p=0,03), comprimento da passada (p=0,01), trabalho mecânico externo (<0,001) e recuperação de energia mecânica (0,009), destacando a importância de considerar a idade em avaliações clínicas. O IMC não influenciou significativamente essas variáveis. Esses achados destacam a necessidade de ajustar as interpretações dos testes clínicos de marcha na esteira em adultos uruguaios de meia- idade (45 a 65 anos).


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Adulto Jovem , Composição Corporal/fisiologia , Caminhada/fisiologia , Teste de Esforço/estatística & dados numéricos , Índice de Massa Corporal , Distribuição por Idade
16.
Int J Equity Health ; 23(1): 195, 2024 Sep 30.
Artigo em Inglês | MEDLINE | ID: mdl-39350286

RESUMO

BACKGROUND: Despite research dedicated to understanding the health profiles and health-related outcomes of Hispanic individuals, the prevailing body of literature frequently homogenizes the Hispanic population, failing to address the role of race in Hispanic health discourse. Thus, the current study applies an intersectional lens to identify health differences and similarities among Hispanic subgroups. METHODS: Sociodemographic characteristics and health domain variables (i.e., health status, health services, and health behaviors) from participants (N = 11,192) were included in the analyses. Bivariate Chi-squared tests examined the relationship between sociodemographic and health domain variables Black Hispanic individuals, white Hispanic individuals, and non-Hispanic Black individuals. RESULTS: Findings suggest that Non-Hispanic Black American individuals reported the highest rates of hypertension (49.09%) and diabetes (19.62%) compared to Black-Hispanic individuals (22.45% and 12.98%) and white Hispanic individuals (22.22% and 8.02%). Black Hispanic individuals reported the greatest proportion of asthma diagnoses (35.10%) and those who saw a doctor in the previous year (95.52%) compared to white Hispanic individuals (26.84%, and 91.10%, respectively) and non-Hispanic Black individuals ( 21.74%, and 94.69%, respectively). CONCLUSION: Specifically, we found that several health behaviors and health-related outcomes significantly varied across different racial/ethnic groups, demonstrating the advantage of an intersectional approach to identify health disparities among racially diverse ethnic groups. PUBLIC HEALTH SIGNIFICANCE: We encourage the development of health care services with an awareness of the complexities resulting from racial differences within the Hispanic diaspora.


Assuntos
Comportamentos Relacionados com a Saúde , Nível de Saúde , Hispânico ou Latino , Adolescente , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Negro ou Afro-Americano , Disparidades nos Níveis de Saúde , Fatores Socioeconômicos , Estados Unidos , Brancos
17.
Int J Qual Stud Health Well-being ; 19(1): 2408831, 2024 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-39356675

RESUMO

PURPOSE: This study aims to contribute to the development of a theoretical model that is useful for enhancing well-being/positive mental health with pedagogical resources that enable the acquisition of skills and knowledge, particularly during Emerging Adulthood. METHODS: This paper enquires into the role of well-being promotion in higher education following the dual-factor model of mental health difficulties and wellbeing. The study narratively reviews the main well-being models and presents a compared theoretical synthesis examining the dimensions that promote or facilitate the presence of well-being using a promotion approach. RESULTS: The study identifies 14 dimensions involved in wellbeing-emotional, psychological and social factors-that can be potentially improved through learning processes. Drawing on empirical and theoretical studies on emerging adult population, a factorial model is proposed. Preliminary factor interactions are examined paying close attention to the cognitive processes that explain or affect their relationship with well-being, the possible correlations between them and particularities of emerging adults. CONCLUSION: Wellbeing factors can be particularly targeted by educational promotion, as they can be developed through learning processes. An integrative model that provides a broad perspective can assist in pedagogical design and defining educational goals for these learning processes involved in wellbeing promotion.


Assuntos
Promoção da Saúde , Saúde Mental , Humanos , Adulto Jovem , Promoção da Saúde/métodos , Estudantes/psicologia , Universidades , Adulto , Emoções , Aprendizagem , Modelos Teóricos , Satisfação Pessoal , Adolescente
18.
Arq Neuropsiquiatr ; 82(10): 1-8, 2024 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-39357852

RESUMO

BACKGROUND: High levels of physical conditioning are associated with improvements in cognitive performance. In this sense, electroencephalographic (ECG) correlates are used to investigate the enhancing role of physical exercise on executive functions. Oscillations in the ß frequency range are proposed to be evident during sensorimotor activity. OBJECTIVE: To investigate the ECG changes influenced by aerobic and resistance exercises performed in an attention task by analyzing the differences in absolute ß power in the prefrontal and frontal regions before, during, and after the oddball paradigm in practitioners and nonpractitioners of physical exercise. METHODS: There were 15 physical activity practitioners (aged 27 ± 4.71) and 15 nonpractitioners (age 28 ± 1.50) recruited. A two-way analysis of variance (ANOVA) was implemented to observe the main effect and the interaction between groups and moments (rest 1, pre-stimulus, and rest 2). RESULTS: An interaction between group and moment factors was observed for Fp1 (p < 0.001); Fp2 (p = 0.001); F7 (p < 0.001); F8 (p < 0.001); F3 (p < 0.001); Fz (p < 0.001); and F4 (p < 0.001). Electrophysiological findings clarified exercisers' specificity and neural efficiency in each prefrontal and frontal subarea. CONCLUSION: Our findings lend support to the current understanding of the cognitive processes underlying physical exercise and provide new evidence on the relationship between exercise and cortical activity.


ANTECEDENTES: Níveis elevados de condicionamento físico estão associados a melhorias no desempenho cognitivo. Nesse sentido, correlatos eletroencefalográficos são utilizados na investigação do papel aprimorador do exercício físico sobre as funções executivas. Tem sido proposto que as oscilações na faixa de frequência ß são evidenciadas durante a atividade sensório-motora. OBJETIVO: Investigar as alterações eletroencefalográficas influenciadas por exercícios aeróbio e resistido realizados em uma tarefa atencional analisando as diferenças da potência absoluta de ß nas regiões pré-frontal e frontal antes, na preparação e depois do paradigma oddball em praticantes e não praticantes de exercício físico. MéTODOS: Foram recrutados 15 praticantes de atividade física (idade 27 ± 4.71) e 15 não praticantes (idade 28 ± 1.50). Uma análise de variância (ANOVA) de duas vias foi implementada para observação do efeito principal e a interação entre os grupos e os momentos (repouso 1, pré-estímulo e repouso 2). RESULTADOS: Uma interação entre os fatores grupo e momento para Fp1 (p < 0,001); Fp2 (p = 0,001); F7 (p < 0,001); F8 (p < 0,001); F3 (p < 0,001); Fz (p < 0,001); e F4 (p < 0,001) foi observada. Os achados eletrofisiológicos esclareceram a especificidade e a eficiência neural dos praticantes de exercício físico em cada subárea pré-frontal e frontal. CONCLUSãO: Nossos achados promovem o entendimento atual dos processos cognitivos subjacentes ao exercício físico e acrescentam novas evidências sobre a relação exercício e atividade cortical.


Assuntos
Ritmo beta , Exercício Físico , Humanos , Adulto , Masculino , Exercício Físico/fisiologia , Análise de Variância , Ritmo beta/fisiologia , Feminino , Adulto Jovem , Atenção/fisiologia , Córtex Pré-Frontal/fisiologia , Cognição/fisiologia , Função Executiva/fisiologia , Fatores de Tempo , Eletroencefalografia , Eletrocardiografia
19.
PLoS One ; 19(10): e0309555, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39441850

RESUMO

The significance of enhancing working conditions for the physical health and performance of workers, particularly female workers, underscores the need for research in this domain and the examination of interventions such as music. Previous studies have yielded diverse outcomes regarding the influence of music on individuals' performance; hence, further research in this area appears imperative. The aim of this study is to explore the impact of music on the cognitive and task performance of female assembly operation operators. This study is an interventional (quasi-experimental) study that involved 81 participants from the female workforce of the medical equipment assembly unit in Isfahan, Iran. The evaluation encompassed task performance, working memory using N-Back test, sustained attention using continues performance test (CPT), degree of sleepiness, and mental fatigue using Flicker Fusion test, along with physiological parameters such as heart rate and blood oxygen level. Participants underwent testing both in the presence of classical music and in a condition without music playback. The provision of background music enhanced the workers' sustained attention and working memory. It led to improved task performance and a reduction in drowsiness. Concerning physiological parameters, it resulted in a slight decrease in heart rate at the end of the work shift and a marginal increase in participants' blood oxygen levels. Background music enhanced working memory (p-value = 0.001), sustained attention (p-value = 0.001), and improved the task performance of workers(p-value = 0.005). Additionally, likely due to increased relaxation, it led to a decrease in heart rate (p-value = 0.001) and an increase in blood oxygen levels (p-value = 0.016). Music also played a role in reducing participants' sleepiness (p-value = 0.001).


Assuntos
Atenção , Cognição , Memória de Curto Prazo , Música , Humanos , Feminino , Música/psicologia , Adulto , Cognição/fisiologia , Memória de Curto Prazo/fisiologia , Atenção/fisiologia , Análise e Desempenho de Tarefas , Fadiga Mental , Equipamentos e Provisões , Frequência Cardíaca/fisiologia , Irã (Geográfico) , Adulto Jovem
20.
PLoS One ; 19(10): e0309425, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39441852

RESUMO

Distractor-induced blindness (DIB) describes a reduced access to a cued visual target-if multiple target-like distractors have been presented beforehand. Previous ERP data suggest a cumulative frontal inhibition triggered by distractors, which affects the updating process of the upcoming target. In the present study, we examine whether the modality of the cue-formerly defined in the visual domain-affects the expression of these neural signatures. 27 subjects were tested in a cross-modal DIB task: Distractors and targets were defined by a transient change of stimuli shape in a random-dot kinematogram. The onset of the target was announced by a rise in amplitude of a sinusoidal tone. Behavioral results confirmed that detection of the target relies on the number of preceding distractor episodes. Replicating previous unimodal results, ERP responses to distractors were characterized by a frontal negativity starting at 100 ms, which increases with an increasing number of distractor episodes. However, the processing-and detection-of the target was not characterized by a more-expressed P3 response, but by an occipital negativity. The current data confirm that the neural signatures of target awareness depend on the experimental setup used: In case of the DIB, the cross-modal setting might lead to a reduction of attentional resources in the visual domain.


Assuntos
Atenção , Eletroencefalografia , Potenciais Evocados , Humanos , Masculino , Feminino , Adulto , Atenção/fisiologia , Adulto Jovem , Estimulação Luminosa , Percepção Visual/fisiologia , Sinais (Psicologia) , Tempo de Reação/fisiologia
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