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1.
J Int Med Res ; 50(1): 3000605211067694, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34994585

RESUMO

We report two suicidal cases of acute methyl ethyl ketone peroxide (MEKP) poisoning. A woman in her late 60s suffered from oral mucosal erosion, functional impairment of the heart, liver and other organs, pulmonary inflammation, elevated inflammatory markers, pleural effusion, hypoproteinemia and metabolic acidosis after oral administration of approximately 50 mL of MEKP. After admission, the patient was administered hemoperfusion four times, 8 mg of betamethasone for 6 days and symptomatic support. Hemoperfusion had an obvious effect on the treatment of oral MEKP poisoning. After discharge, the patient developed progressive dysphagia and secondary esophageal stenosis. Supplementary feeding was administered with a gastrostomy tube after the patient was completely unable to eat. A man in his mid-40s developed oropharyngeal mucosal erosion, bronchitis and esophageal wall thickening after oral administration of 40 ml MEKP. After receiving total gastrointestinal dispersal, 80 mg of methylprednisolone was administered for 7 days, and symptomatic supportive treatment was provided. Slight dysphagia was observed after discharge, and there was no major effect on the quality of life. Patients with acute oral MEKP poisoning should be followed up regularly to observe its long-term effects on digestive tract corrosion and stenosis.


Assuntos
Hemoperfusão , Peróxidos , Butanonas , Feminino , Humanos , Fígado , Masculino , Qualidade de Vida
2.
Int J Nurs Educ Scholarsh ; 18(1)2022 Jan 07.
Artigo em Inglês | MEDLINE | ID: mdl-34995025

RESUMO

OBJECTIVES: Studies on quality of life (QoL) and academic resilience among nursing students during the Coronavirus disease (COVID-19) pandemic remain underreported. This study investigated the relationship between nursing students' QoL and academic resilience and their predictors during the COVID-19 pandemic. METHODS: A descriptive survey, cross-sectional study that used two self-reported questionnaire scales to evaluate the QoL and academic resilience of Filipino nursing students (n=924). Chi-squared test and multiple regression were used to analyze the data. RESULTS: There was no significant association between the QoL and academic resilience to participants' profile variables. Gender and year level of nursing students were significant predictors of QoL and academic resilience. CONCLUSIONS: Our study concludes that a better understanding of the QoL and academic resilience, which are two distinct concepts critical in developing a student's mental well-being, will help stakeholders in nursing education establish effective psychoeducation programs for nursing students.


Assuntos
COVID-19 , Estudantes de Enfermagem , Estudos Transversais , Humanos , Pandemias , Qualidade de Vida , SARS-CoV-2
3.
Am J Occup Ther ; 76(1)2022 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-34997839

RESUMO

IMPORTANCE: Unplanned hospital readmissions can profoundly affect older adults' quality of life and the financial status of skilled nursing facilities (SNFs). Although many clinical practices focus on reforming these issues, occupational therapy's involvement remains unclear. OBJECTIVE: To explore clinical practices aimed at reducing hospital readmissions of older adults pursuing postacute care (PAC) at SNFs and describe how they align with occupational therapy's scope of practice. DATA SOURCES: We searched CINAHL, Scopus, PubMed, and OTseeker for articles published from January 2011 to February 2020. Study Selection and Data Collection: We conducted a scoping review of peer-reviewed articles with functional outcomes of clinical practices reducing unplanned hospital readmissions of patients older than age 65 yr pursuing PAC services in SNFs. Trained reviewers completed the title and abstract screens, full-text reviews, and data extraction. FINDINGS: Thirteen articles were included and focused on five areas: risk and medical disease management and follow-up, hospital-to-SNF transition, enhanced communication and care, function, and nutrition. Early coordination of care and early identification of patients' needs and risk of readmission were common features. All clinical practices aligned with occupational therapy domains and processes, but only 1 study specified occupational therapy as part of the research team. CONCLUSIONS AND RELEVANCE: Comprehensive, multipronged clinical practices encompassing care coordination and early identification and management of acute conditions are critical in reducing preventable readmissions among older adults pursuing PAC services in SNFs. Further research is needed to support occupational therapy's value in preventing hospital readmissions of older adults in this setting. What This Article Adds: This scoping review maps the presence of occupational therapy's domains and processes in the clinical practices that reduce hospital readmissions of older adults pursuing PAC services in SNFs. Findings provide occupational therapy practitioners with opportunities to assume roles beyond direct patient care, research, advocate, and publish more, thereby increasing their presence and adding value to occupational therapy interventions that reduce hospital readmissions.


Assuntos
Readmissão do Paciente , Instituições de Cuidados Especializados de Enfermagem , Idoso , Humanos , Alta do Paciente , Qualidade de Vida , Cuidados Semi-Intensivos
4.
Rev Alerg Mex ; 69 Suppl 1: s24-s30, 2022.
Artigo em Espanhol | MEDLINE | ID: mdl-34998307

RESUMO

Air pollution, climate change, and the decrease of biological diversity are major threats to human health. In the past decades, an increase in allergic diseases, including asthma and rhinoconjunctivitis, has been observed. Up to 40 % of the world population may have an allergic disease, which represents a significant impact on the quality of life of those who suffer from it, and environmental pollution is one of the causes of its presentation. Air pollution causes significant morbidity and mortality in patients with inflammatory airway diseases such as allergic rhinitis, chronic rhinosinusitis, asthma, and chronic obstructive pulmonary disease. Oxidative stress in patients with respiratory diseases can induce eosinophilic inflammation in the airways, increase atopic allergic sensitization, and rise susceptibility to infections. Climate change has influenced exposure to extramural allergens and it is associated with exacerbations of respiratory diseases in the upper and lower airway. The interaction of indoor and outdoor environmental exposure and host factors can affect the development and progression of lifelong allergic diseases. The decrease of exposure to air pollutants has been associated with a favorable response in respiratory health, which is why it is necessary to implement measures that contribute to an improvement in air quality.


Assuntos
Poluentes Atmosféricos , Poluição do Ar , Asma , Rinite Alérgica , Poluentes Atmosféricos/efeitos adversos , Poluição do Ar/efeitos adversos , Alérgenos , Asma/epidemiologia , Asma/etiologia , Humanos , Qualidade de Vida , Rinite Alérgica/epidemiologia , Rinite Alérgica/etiologia
5.
BMC Psychiatry ; 22(1): 25, 2022 01 10.
Artigo em Inglês | MEDLINE | ID: mdl-35012486

RESUMO

BACKGROUND: The COVID-19 pandemic and its associated national lockdowns have been linked to deteriorations in mental health worldwide. A number of studies analysed changes in mental health indicators during the pandemic; however, these studies generally had a small number of timepoints, and focused on the initial months of the pandemic. Furthermore, most studies followed-up the same individuals, resulting in significant loss to follow-up and biased estimates of mental health and its change. Here we report on time trends in key mental health indicators amongst Danish adults over the course of the pandemic (March 2020 - July 2021) focusing on subgroups defined by gender, age, and self-reported previously diagnosed chronic and/or mental illness. METHODS: We used time-series data collected by Epinion (N=8,261) with 43 timepoints between 20 March 2020 and 22 July 2021. Using a repeated cross-sectional study design, independent sets of individuals were asked to respond to the Copenhagen Corona-Related Mental Health questionnaire at each timepoint, and data was weighted to population proportions. The six mental health indicators examined were loneliness, anxiety, social isolation, quality of life, COVID-19-related worries, and the mental health scale. Gender, age, and the presence of previously diagnosed mental and/or chronic illness were used to stratify the population into subgroups for comparisons. RESULTS: Poorer mental health were observed during the strictest phases of the lockdowns, whereas better outcomes occurred during reopening phases. Women, young individuals (<34 yrs), and those with a mental- and/or chronic illness demonstrated poorer mean time-series than others. Those with a pre-existing mental illness further had a less reactive mental health time-series. The greatest differences between women/men and younger/older age groups were observed during the second lockdown. CONCLUSIONS: People with mental illness have reported disadvantageous but stable levels of mental health indicators during the pandemic thus far, and they seem to be less affected by the factors that result in fluctuating time-series in other subgroups.


Assuntos
COVID-19 , Adulto , Idoso , Controle de Doenças Transmissíveis , Estudos Transversais , Dinamarca/epidemiologia , Feminino , Humanos , Masculino , Saúde Mental , Pandemias , Qualidade de Vida , SARS-CoV-2
6.
BMC Gastroenterol ; 22(1): 18, 2022 Jan 11.
Artigo em Inglês | MEDLINE | ID: mdl-35016615

RESUMO

BACKGROUND: In this trial, we investigated the effect of a group-based education program on gastrointestinal (GI) symptoms and quality of life (QOL) in patients with celiac disease (CD). METHOD: In the present study, 130 patients with CD who were on a GFD for at least 3 months, randomly assigned to receive group-based education (n = 66) or routine education in the celiac clinic (n = 64) for 3 months. We assessed gastrointestinal symptoms and quality of life using the gastrointestinal symptom rating scale (GSRS) questionnaire and SF-36 questionnaire at baseline and 3 months after interventions. RESULTS: The mean age of the participants was 37.57 ± 9.59 years. There were no significant differences between the two groups regarding the baseline values. Results showed that the mean score of total GSRS score in the intervention group was significantly lower compared with the control group 3 months post-intervention (p = 0.04). Also, there was a significant difference in the mean score of SF-36 between the two groups 3 months post-intervention (p = 0.02). CONCLUSION: Results showed that group-based education was an effective intervention in patients with celiac disease to improve gastrointestinal symptoms and quality of life. Trial registration IRCT code: IRCT20080904001197N21; registration date: 5/23/2019.


Assuntos
Doença Celíaca , Qualidade de Vida , Adulto , Doença Celíaca/terapia , Dieta Livre de Glúten , Humanos , Pessoa de Meia-Idade , Inquéritos e Questionários
7.
BMC Med Educ ; 22(1): 16, 2022 Jan 04.
Artigo em Inglês | MEDLINE | ID: mdl-34983481

RESUMO

BACKGROUND: Nearly all U.S. medical students engage in a 4-8 week period of intense preparation for their first-level licensure exams, termed a "dedicated preparation period" (DPP). It is widely assumed that student well-being is harmed during DPPs, but evidence is limited. This study characterized students' physical, intellectual, emotional, and social well-being during DPPs. METHODS: This was a cross-sectional survey sent electronically to all second-year students at four U.S. medical schools after each school's respective DPP for USMLE Step 1 or COMLEX Level 1 in 2019. Survey items assessed DPP characteristics, cost of resources, and perceived financial strain as predictors for 18 outcomes measured by items with Likert-type response options. Open-ended responses on DPPs' influence underwent thematic analysis. RESULTS: A total of 314/750 (42%) students completed surveys. DPPs lasted a median of 7 weeks (IQR 6-8 weeks), and students spent 70 h/week (IQR 56-80 h/week) studying. A total of 62 (20%) reported experiencing a significant life event that impacted their ability to study during their DPPs. Most reported 2 outcomes improved: medical knowledge base (95%) and confidence in ability to care for patients (56%). Most reported 9 outcomes worsened, including overall quality of life (72%), feeling burned out (77%), and personal anxiety (81%). A total of 25% reported paying for preparation materials strained their finances. Greater perceived financial strain was associated with worsening 11 outcomes, with reported amount spent associated with worsening 2 outcomes. Themes from student descriptions of how DPPs for first-level exams influenced them included (1) opportunity for synthesis of medical knowledge, (2) exercise of endurance and self-discipline required for professional practice, (3) dissonance among exam preparation resource content, formal curriculum, and professional values, (4) isolation, deprivation, and anguish from competing for the highest possible score, and (5) effects on well-being after DPPs. CONCLUSIONS: DPPs are currently experienced by many students as a period of personal and social deprivation, which may be worsened by perceived financial stress more than the amount of money they spend on preparation materials. DPPs should be considered as a target for reform as medical educators attempt to prevent student suffering and enhance their well-being.


Assuntos
Educação de Graduação em Medicina , Estudantes de Medicina , Estudos Transversais , Avaliação Educacional , Humanos , Licenciamento em Medicina , Qualidade de Vida
8.
Trials ; 23(1): 12, 2022 Jan 04.
Artigo em Inglês | MEDLINE | ID: mdl-34983621

RESUMO

BACKGROUND: Men with localized prostate cancer often experience urinary, sexual, bowel, and hormonal symptoms; general distress; pain; fatigue; and sleep disturbance. For men in an intimate relationship, these symptoms disrupt couples' relationships and intimacy. The symptoms also reduce quality of life for both men and their partners, who are often their primary caregivers. Management of the negative effects of cancer and its treatment is a significantly under-addressed supportive care need for these men and their intimate partners. To address these unmet supportive care needs, our interdisciplinary team developed and pilot tested the usability and feasibility of an evidence-based, couple-focused, tailored eHealth intervention, "Prostate Cancer Education & Resources for Couples" (PERC). Based on the adapted stress and coping theoretical framework and developed with stakeholder involvement, PERC aims to improve quality of life for both men and their partners by enhancing their positive appraisals, self-efficacy, social support, and healthy behaviors for symptom management. METHODS: We will test the efficacy of PERC using a population-based, geographically and demographically diverse cohort in a randomized controlled trial. Primary aim: Assess if patients and partners receiving PERC will report greater improvement in their cancer-related quality of life scores than those in the control group (usual care plus the National Cancer Institute prostate cancer website) at 4, 8, and 12 months post-baseline. Secondary aim: Test if patients and partners in PERC will report significantly more positive appraisals and higher levels of coping resources at follow-ups than those in the control group. Exploratory aim: Determine if patient race and ethnicity, education, type of treatment, or couples' relationship quality moderate the effects of PERC on patient and partner QOL at follow-ups. DISCUSSION: This study will provide a novel model for self-managing chronic illness symptoms that impact couples' relationships, intimacy, and quality of life. It addresses the National Institute of Nursing Research's goal to develop and test new strategies for symptom self-management to help patients and caregivers better manage their illness and improve quality of life. It also responds to calls for programs from the Institute of Medicine and American Cancer Society to address treatment-related effects and improve survivors' QOL. TRIAL REGISTRATION: CT.gov NCT03489057.


Assuntos
Neoplasias da Próstata , Autogestão , Telemedicina , Humanos , Masculino , Neoplasias da Próstata/diagnóstico , Neoplasias da Próstata/terapia , Qualidade de Vida , Ensaios Clínicos Controlados Aleatórios como Assunto , Cônjuges
9.
Curr Protoc ; 2(1): e333, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34985830

RESUMO

Advanced solid tumors often metastasize to bone. Once established in bone, these tumors can induce bone destruction resulting in decreased quality of life and increased mortality. Neither 2D in vitro models nor 3D animal models sufficiently recapitulate the human bone-tumor microenvironment needed to fully understand the complexities of bone metastasis, highlighting the need for new models. A 3D in vitro humanized model of tumor-induced bone disease was developed by dynamically culturing human osteoblast, osteoclast, and metastatic cancer cells together within tissue-engineered bone constructs. Cell-mediated resorption can be observed by micro-computed tomography and can be quantified by change in mass. Taken together, these data can be used to investigate whether the metastatic cancer cells included in the model have the potential to drive osteoclastogenesis and cell-mediated resorption in vitro. © 2022 Wiley Periodicals LLC. Basic Protocol 1: Fabricating bone-like scaffolds Basic Protocol 2: Preparing cells for the humanized model of TIBD Basic Protocol 3: Crafting a 3D in vitro humanized model of TIBD.


Assuntos
Neoplasias Ósseas , Qualidade de Vida , Animais , Reatores Biológicos , Humanos , Perfusão , Microambiente Tumoral , Microtomografia por Raio-X
10.
Acta Neurol Taiwan ; 31(1): 24-35, 2022 Jan 25.
Artigo em Inglês | MEDLINE | ID: mdl-34988951

RESUMO

PURPOSE: Quality of life (QoL) is considered as an important criterion for therapeutic effectiveness. Therefore, the present study aimed to validate the Persian version of the Hamburg Quality of Life Questionnaire in Multiple Sclerosis (HAQUAMS) for use in Iranian people with MS. METHODS: In a cross-sectional study, 158 people with MS were selected through the census sampling method. The construct validity of the Persian version of HAQUAMS was first evaluated by a confirmatory factor analysis (CFA) in AMOS-22 software, and then the internal consistency reliability and the item-total score correlations were calculated for each subscale by the SPSS-22. RESULTS: The CFA and output results indicated that the HAQUAMS with a five-factor structure among the Iranian MS patients had a good construct validity if an item was eliminated and a number of covariance errors between items were released (RMSEA is euqal to 0.069). The internal consistency of HAQUAMS subscales was acceptable to excellent (alpha is euqal to 0.81 to 0.91). The analysis of item-total score correlation for determining the construct validity of HAQUAMS indicated that all items of the questionnaire had a moderate to strong positive correlation with their subscales (P less than 0.0001, r is euqal to 0.41 to 0.89). The correlation of total scores of HAQUAMS and the Beck Depression Inventory-short form (BDI-13) was equal to 0.74 (P less than 0.0001), indicating good concurrent criterion validity. CONCLUSION: The Persian version of the HAQUAMS with a five-factor construct had acceptable validity and reliability and could be used for measurement of the health related QoL in Iranian people with MS.


Assuntos
Esclerose Múltipla , Qualidade de Vida , Estudos Transversais , Humanos , Irã (Geográfico) , Psicometria , Reprodutibilidade dos Testes , Inquéritos e Questionários
11.
Agri ; 34(1): 47-53, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34988960

RESUMO

OBJECTIVES: Headache is one of the most common health problems, and it severely reduces the quality of life. The present study examines the efficacy of greater occipital nerve (GON) block in patients monitored for primary headaches. METHODS: The present study includes 53 patients monitored by the headache outpatient clinic from March 2017 to June 2018, evaluates them for headache type, attack duration, attack frequency, severity of pain, and analgesic intake and compares the initial values with the follow-up values at months 1, 3, and 6. RESULTS: The study group comprises 36 episodic migraine cases, 12 tension-type headache (TTH) cases, 4 chronic migraine cases, and 1 cluster headache case. In migraine group, VAS scores, attack durations, and the mean value of monthly number of attacks and analgesics taken significantly decrease compared to initial values at the end of the 6-month follow-up period. In TTH group, VAS scores, attack durations, and the mean value of monthly number of attacks and analgesics taken significantly decrease compared to initial values at the end of the 3-month follow-up period. Since only 2 of 12 patients completed the 6-month follow-up, although there was a decrease in the 6-month data, it was found to be statistically insignificant. CONCLUSION: Repetitive GON block is an effective treatment method for migraine and TTH.


Assuntos
Transtornos de Enxaqueca , Bloqueio Nervoso , Cefaleia do Tipo Tensional , Cefaleia , Humanos , Qualidade de Vida
12.
BMC Musculoskelet Disord ; 23(1): 23, 2022 Jan 03.
Artigo em Inglês | MEDLINE | ID: mdl-34980045

RESUMO

BACKGROUND: Knee osteoarthritis (OA) is a debilitating condition affecting human body biomechanics and quality of life. Current standard care for knee OA leads to trivial improvement and entails multiple adverse effects or complications. Recently, investigational cell therapies injected intra-articularly, such as bone marrow aspirate concentrate (BMAC) and platelet-rich plasma (PRP), have shown safety and therapeutic potency providing patients with pain relief. In the current retrospective comparative study, we investigated the differences in pain and functional improvements in patients with symptomatic knee OA receiving intra-articular injections of BMAC vs PRP. METHODS: Pain and functionality scores were measured at baseline and at different time points post-injection over 12 months, using 3 self-administered, clinically validated questionnaires: the visual analogue scale (VAS) for assessing pain intensity, the knee injury and osteoarthritis outcome score (KOOS) for evaluating functionality and knee-related quality of life, and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) for evaluating physical function. The repeated-measures general linear model with Sidak test for pairwise comparisons was used to investigate the influence of the treatment on the score evolution within groups (between baseline and each time point) and between groups (overall). RESULTS: The BMAC group (n = 26 knees) significantly improved in VAS, KOOS, and WOMAC scores between baseline and 12 months (57.4, 75.88, and 73.95% mean score improvement, respectively). In contrast, the PRP group (n = 13 knees) witnessed nonsignificant improvement in all scores. BMAC, in comparison to PRP, induced significant improvement in outcomes by 29.38% on the VAS scale, 53.89% on the KOOS scale, and 51.71% on the WOMAC scale (P < .002, P < .01, P < .011, respectively). CONCLUSIONS: Intra-articular autologous BMAC injections are safe, effective in treating pain, and ameliorate functionality in patients with symptomatic knee OA to a greater extent than PRP injections. Intra-articular autologous BMAC therapy is safe and provides more relief to patients with symptomatic knee osteoarthritis compared to PRP therapy.


Assuntos
Osteoartrite do Joelho , Plasma Rico em Plaquetas , Medula Óssea , Humanos , Ácido Hialurônico/uso terapêutico , Injeções Intra-Articulares , Osteoartrite do Joelho/tratamento farmacológico , Osteoartrite do Joelho/terapia , Qualidade de Vida , Estudos Retrospectivos , Resultado do Tratamento
13.
BMC Palliat Care ; 21(1): 4, 2022 Jan 04.
Artigo em Inglês | MEDLINE | ID: mdl-34980088

RESUMO

BACKGROUND: An integrated care network between emergency, specialized and primary care services can prevent repeated hospitalizations and the institutionalized death of terminally ill patients in palliative care (PC). To identify the perception of health professionals regarding the concept of PC and their care experiences with this type of patient in a pre-hospital care (PHC) service in Brazil. METHODS: Study with a qualitative approach, of interpretative nature, based on the perspective of Ricoeur's Dialectical Hermeneutics. RESULTS: Three central themes emerged out of the professionals' speeches: (1) unpreparedness of the team, (2) decision making, and (3) dysthanasia. CONCLUSIONS: It is necessary to invest in professional training associated with PC in the home context and its principles, such as: affirming life and considering death as a normal process not rushing or postponing death; integrating the psychological and spiritual aspects of patient and family care, including grief counseling and improved quality of life, adopting a specific policy for PC that involves all levels of care, including PHC, and adopt a unified information system, as well as more effective procedures that favor the respect for the patients' will, without generating dissatisfaction to the team and the family.


Assuntos
Cuidados Paliativos , Qualidade de Vida , Brasil , Hospitais , Humanos , Pesquisa Qualitativa
14.
BMC Palliat Care ; 21(1): 5, 2022 Jan 04.
Artigo em Inglês | MEDLINE | ID: mdl-34980096

RESUMO

BACKGROUND: Older advanced stage cancer patients, with changes in nutritional status, represent an important demand for palliative care. The aim was to determine the effects of 4 weeks of chocolate consumption on the nutritional status of older cancer patients in palliative care. METHODS: Older cancer patients in palliative care with ambulatory (n = 46) monitoring were randomized to control (CG, n = 15), intervention with 55% cocoa chocolate (IG1, n = 16) and intervention with white chocolate (IG2, n = 15) groups and evaluated before and after 4 weeks for nutritional status (primary outcome), evaluated by the Mini Nutritional Assessment tool (MNA). Food consumption, anthropometry, body composition, laboratory parameters and quality of life (QL) with the European Organization for the Research and Treatment of Cancer instrument were also evaluated. RESULTS: IG1 progressed with increased screening (estimated difference [95% CI]: - 1.3 [- 2.2;-0.4], p < 0.01), and nutritional (estimated difference [95% CI]: - 1.3 [- 2.5;-0.1], p = 0.04) scores on the MNA, with no change in anthropometry and body composition. Regarding antioxidant capacity, reduced glutathione levels increased (estimated difference [95% CI]: - 0.8 [- 1.6;-0.02], p = 0.04) and malondealdehyde levels decreased in IG2 (estimated difference [95% CI]:+ 4.9 [+ 0.7;+ 9.1], p = 0.02). Regarding QL, functionality improved in IG1, with higher score in the functional domain (estimated difference [95% CI]:-7.0 [- 13.3;-0.7], p = 0.03). CONCLUSIONS: The consumption of chocolate with a greater cocoa content may contribute to the improvement of the nutritional status and functionality among older cancer patients in palliative care. The consumption of white chocolate was associated with improved oxidative stress. TRIAL REGISTRATION: A randomized clinical trial (ClinicalTrials.gov NCT04367493 ).


Assuntos
Chocolate , Neoplasias , Humanos , Neoplasias/complicações , Neoplasias/terapia , Estado Nutricional , Cuidados Paliativos , Qualidade de Vida
15.
BMC Med Educ ; 22(1): 11, 2022 Jan 03.
Artigo em Inglês | MEDLINE | ID: mdl-34980110

RESUMO

BACKGROUND: The Internet as a communication tool is an essential component of daily life. Nowadays, problematic Internet use (PIU) has led to various psychosocial problems that can indirectly lead to oral diseases due to neglect of healthy behaviors. Also, college students are a large proportion of Internet users. The present study aimed to determine the association between problematic Internet use and oral health-related quality of life (OHRQoL) among medical and dental students. METHODS: A cross-sectional descriptive-analytical study was conducted on medical and dental students in the first and second years of education (basic sciences courses) at the Golestan University of Medical Sciences, Iran, between January and July 2020. The data collection process was carried out in the following sequence: questionnaire on demographic characteristics (age, gender, marital status, academic field, and year); Problematic Internet Use Questionnaire (PIUQ); and Oral Health Impact Profile (OHIP-14) questionnaire. RESULTS: Among 268 medical and dental students, 171 students (63.81%) [95% confidence interval: 58.02%- 69.60%] had problematic Internet use. The mean PIU score in the first-year was significantly higher than the second-year students. In addition, 65% of single students and 25% of married subjects were dealing with PIU. The statistical difference between mean OHIP scores among PIU students (12.5 ± 2.9), with average Internet usage (7.39 ± 6.6), was significant. The Spearman correlation coefficient between PIU and OHIP was 0.309 and significant (P-value < 0.000001). It indicates that students with higher PIU showed higher OHIP scores. CONCLUSION: The present study showed that problematic Internet use was significantly associated with oral health-related quality of life (OHRQoL) among first and second-year medical and dental students. Thus, the students with problematic Internet use experienced a poorer oral health-related quality of life than average Internet users. Furthermore, appropriate preventive and interventional strategies need to be developed to encourage rational use of the Internet to protect the users' oral health, especially among medical and dental students.


Assuntos
Comportamento Aditivo , Qualidade de Vida , Comportamento Aditivo/epidemiologia , Estudos Transversais , Humanos , Internet , Uso da Internet , Estudantes de Odontologia , Inquéritos e Questionários
16.
Trials ; 23(1): 6, 2022 Jan 03.
Artigo em Inglês | MEDLINE | ID: mdl-34980197

RESUMO

BACKGROUND: Knee osteoarthritis (KOA) is a common degenerative disease that causes pain, functional impairment, and reduced quality of life. Resistance training is considered as an effective approach to reduce the risk of muscle weakness in patients with KOA. Blood flow restriction (BFR) with low-load resistance training has better clinical outcomes than low-load resistance training alone. However, the degree of BFR which works more effectively with low-load resistance training has not been determined. The purpose of this study is to evaluate the effectiveness of different degrees of BFR with low-load resistance training in patients with KOA on pain, self-reported function, physical function performance, muscle strength, muscle thickness, and quality of life. METHODS: This is a study protocol for a randomized, controlled trial with blinded participants. One hundred individuals will be indiscriminately assigned into the following groups: two training groups with a BFR at 40% and 80% limb occlusion pressure (LOP), a training group without BFR, and a health education group. The three intervention groups will perform strength training for the quadriceps muscles twice a week for 12 weeks, while the health education group will attend sessions once a week for 12 weeks. The primary outcome is pain. The secondary outcomes include self-reported function, physical function performance, muscle strength of the knee extensors, muscle mass of the quadriceps, quality of life, and adverse events. Intention-to-treat analysis will be conducted for individuals who withdraw during the trial. DISCUSSION: Previous studies have shown that BFR with low-load resistance training is more effective than low-load resistance training alone; however, a high degree of BFR may cause discomfort during training. If a 40% LOP for BFR could produce similar clinical outcomes as an 80% LOP for BFR, resistance training with a low degree of BFR can be chosen for patients with KOA who are unbearable for a high degree of BFR. TRIAL REGISTRATION: Chinese Clinical Trial Registry ChiCTR2000037859 ( http://www.chictr.org.cn/edit.aspx?pid=59956&htm=4 ). Registered on 2 September 2020.


Assuntos
Osteoartrite do Joelho , Treinamento de Força , Humanos , Força Muscular , Osteoartrite do Joelho/diagnóstico por imagem , Osteoartrite do Joelho/terapia , Músculo Quadríceps , Qualidade de Vida , Ensaios Clínicos Controlados Aleatórios como Assunto , Fluxo Sanguíneo Regional
17.
Int J Qual Stud Health Well-being ; 17(1): 2018769, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34978276

RESUMO

PURPOSE: Symptoms and medication use in patients with Parkinson's disease (PD) affect the quality of life of patients and caregivers, yet prior research seldom focused on their experiences with medications. This study explored comprehensive living and medication experience from patients with PD and their caregivers. METHODS: Patients diagnosed with PD for ≥2 years, with or without their caregivers, were recruited from an outpatient clinic in Taiwan. Semi-structured in-depth interviews were conducted based on the Common Sense Model. A qualitative content analysis was used to identify salient themes from verbatim transcripts. RESULTS: In total, 15 patients and eight caregivers were interviewed. Five themes were derived: (1) symptoms and help-seeking behaviours before a diagnosis, (2) emotional impacts and life adaptations after a PD diagnosis, (3) life affected by medications, (4) experiences of caregivers in taking care of PD patients, and (5) communication between doctors and patients. CONCLUSIONS: Patients frequently adjusted their daily schedules to live with PD and the medication side effects. Caregivers struggle to overcome caring burdens and to stay positive to support patients. More attention on providing medication information, mental support, and communication between stakeholders is needed to improve the quality of life of patients and caregivers.


Assuntos
Doença de Parkinson , Médicos , Cuidadores , Comunicação , Humanos , Doença de Parkinson/tratamento farmacológico , Qualidade de Vida
18.
J Med Case Rep ; 16(1): 3, 2022 Jan 04.
Artigo em Inglês | MEDLINE | ID: mdl-34980241

RESUMO

CONTEXT: Dermatomyositis is a rare autoimmune disease characterized by noninfectious inflammatory damage of skin and predominant muscles in the belts. It is believed to be associated with about 1 in 1000 cases of nasopharyngeal carcinoma. This association has been described for locally advanced stages II and III nasopharyngeal carcinoma. It has rarely been described in the early stages (stage I). CASE PRESENTATION: A 65-year-old Moroccan patient residing in Casablanca, with no particular history was referred to the Mohamed VI Center for the treatment of cancers of the University Hospital Center IBN ROCHD in Casablanca, for treatment of nasopharyngeal cancer. He was admitted in poor general condition, performance status 3, with erythema on the face, neck, and extremities. The diagnosis of paraneoplastic dermatomyositis was made owing to progressive muscle weakness and elevation of muscle enzymes associated with the typical rash of the face and hands. He received corticosteroid therapy and then radiotherapy to the nasopharynx with good clinical outcome, disappearance of skin lesions, and recovery of muscle strength. CONCLUSIONS: We report this case of dermatomyositis in early-stage nasopharyngeal carcinoma, which is a rarely described entity. Rapid treatment of dermatomyositis improved the patient's quality of life and enabled him to support specific cancer treatments. This can be used as an element of early diagnosis and monitoring after treatment.


Assuntos
Dermatomiosite , Neoplasias Nasofaríngeas , Síndromes Paraneoplásicas , Idoso , Autoanticorpos , Dermatomiosite/diagnóstico , Humanos , Masculino , Carcinoma Nasofaríngeo , Neoplasias Nasofaríngeas/complicações , Neoplasias Nasofaríngeas/diagnóstico , Síndromes Paraneoplásicas/diagnóstico , Síndromes Paraneoplásicas/etiologia , Qualidade de Vida
19.
J Coll Physicians Surg Pak ; 32(1): 68-74, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34983151

RESUMO

Chronic obstructive pulmonary disease (COPD) is the third leading cause of mortality and morbidity across the Globe. A meta-analysis was conducted to determine the effectiveness of different modes of resistance training on FEV1 and functional exercise capacity among COPD patients. Data bases of Cochrane, PEDro, Embase, CINAHL, PubMed and Google Scholar were searched seeking research articles of interest. All those studies were included in which effect of resistance training was determined on FEV1 and functional exercise capacity of COPD patients and published in English language. All those studies that predated to 2011 were excluded from the review. A sample of 180 COPD patients was included in 5 RCTs. Results of the study demonstrated that resistance training has a mild pool effect in increasing FEV1 with an effect size of (SMD) of 0.160 (95% CI of -0.840 to 0.521) calculated at random effect model, I2 = 62.99% (95% CI of 0.00 to 89.42); whereas, functional exercise capacity demonstrated large pool effect size 0.886 (95% CI of 0.401 to 1.371) with I2 = 0.0 (95% CI of 0.00 to 0.00). The study concludes that there is a small to large impact of resistance exercises in improving functional exercise capacity and forced expiratory volume. Key Words: Resistance training, 6-minute walk test 6MWT, Chronic obstructive pulmonary disease, Functional exercise capacity, Forced expiratory volume.


Assuntos
Doença Pulmonar Obstrutiva Crônica , Treinamento de Força , Tolerância ao Exercício , Volume Expiratório Forçado , Humanos , Qualidade de Vida
20.
BMC Surg ; 22(1): 11, 2022 Jan 08.
Artigo em Inglês | MEDLINE | ID: mdl-34998366

RESUMO

BACKGROUND: The symptomatic (swelling and pain) salivary gland obstructions are caused by sialolithiasis and salivary duct stenosis, negatively affecting quality of life (QOL), with almost all candidates for clinical measures and minimally invasive sialendoscopy. The impact of sialendoscopy treatment on the QOL has been little addressed nowadays. The objective is to prospectively evaluate the impact of sialendoscopy on the quality of life of patients undergoing sialendoscopy due to benign salivary obstructive diseases, measured through QOL questionnaires of xerostomia degree, the oral health impact profile and post sialendoscopy satisfaction questionnaires. RESULT: 37 sialendoscopies were included, most young female; there were 64.5% sialolithiasis and 35.4% post-radioiodine; with 4.5 times/week painful swelling symptoms and 23.5 months symptom duration. The pre- and post-sialendoscopy VAS values were: 7.42 to 1.29 (p < 0.001); 86.5% and 89.2% were subjected to sialendoscopy alone and endoscopic dilatation respectively; 80.6% reported improved symptoms after sialendoscopy in the sialolithiasis clinic (p < 0.001). The physical pain and psychological discomfort domain scores were mostly impacted where sialendoscopy provided relief and improvement (p < 0.001). We found a positive correlation between sialendoscopy and obstructive stone disease (p < 0.001) and no correlation in sialendoscopy satisfaction in xerostomia patients (p = 0.009). CONCLUSIONS: We found improved symptoms with overall good satisfaction after sialendoscopy correlated with stones; and a negative correlation between xerostomia. Our findings support the evident indication of sialendoscopy for obstructive sialolithiasis with a positive impact on QOL and probably a relative time-dependent indication for stenosis/other xerostomia causes that little improved QOL satisfaction. LEVEL OF EVIDENCE: 2b-Prospective non-randomized study. TRIAL REGISTRATION: WHO Universal Trial Number (UTN): U1111-1247-7028; Brazilian Clinical Trials Registry (ReBeC): RBR-6p8zfs.


Assuntos
Cálculos das Glândulas Salivares , Sialadenite , Endoscopia , Feminino , Humanos , Radioisótopos do Iodo , Estudos Prospectivos , Qualidade de Vida , Estudos Retrospectivos , Resultado do Tratamento
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