A synthetic, nitrogenated antimetastatic and anti-angiogenic compound with low toxicity in vivo.

Cerutti, M L; D'Orio, E; Davel, L; Colombo, L; Parma, P; Diament, M; Stillitani, I; Gelpi, M E; Leicach, S R; Eiján, A M

Cerutti, M L; D'Orio, E; Davel, L; Colombo, L; Parma, P; Diament, M; Stillitani, I; Gelpi, M E; Leicach, S R; Eiján, A M.

Affiliation

Cerutti ML; Area Investigación, Instituto de Oncología <Angel H. Roffo>, Buenos Aires, Argentina.

Int J Oncol ; 14(3): 585-91, 1999 Mar.

Article in En | MEDLINE | ID: mdl-10024695

Subject(s)

Antineoplastic Agents/pharmacology; Inositol/analogs & derivatives; Purines/pharmacology; Adenocarcinoma/pathology; Animals; Antineoplastic Agents/chemical synthesis; Antineoplastic Agents/therapeutic use; Antineoplastic Agents/toxicity; Cell Division/drug effects; Drug Screening Assays, Antitumor; Female; Inositol/chemical synthesis; Inositol/pharmacology; Inositol/toxicity; Iodine Radioisotopes; Mammary Neoplasms, Experimental/pathology; Mice; Mice, Inbred BALB C; Neoplasm Metastasis/prevention & control; Neovascularization, Pathologic/prevention & control; Purines/chemical synthesis; Purines/toxicity; Tissue Distribution; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Purines / Inositol / Antineoplastic Agents Limits: Animals Language: En Journal: Int J Oncol Year: 1999 Document type: Article

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