Improved functional recovery of ischemic rat hearts due to singlet oxygen scavengers histidine and carnosine.

Lee, J W; Miyawaki, H; Bobst, E V; Hester, J D; Ashraf, M; Bobst, A M

Lee, J W; Miyawaki, H; Bobst, E V; Hester, J D; Ashraf, M; Bobst, A M.

Affiliation

Lee JW; Department of Chemistry, University of Cincinnati, OH 45221, USA.

J Mol Cell Cardiol ; 31(1): 113-21, 1999 Jan.

Article in En | MEDLINE | ID: mdl-10072720

Subject(s)

Carnosine/therapeutic use; Histidine/therapeutic use; Reperfusion Injury/therapy; Animals; Coronary Vessels/drug effects; Cyclic N-Oxides/analysis; Dose-Response Relationship, Drug; Ethanol/pharmacology; Fluorescent Dyes/analysis; Heart Rate/drug effects; Magnetic Resonance Spectroscopy; Male; Mannitol/pharmacology; Myocardium/chemistry; Nitric Oxide/analysis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species/metabolism; Recovery of Function; Rose Bengal/analysis; Sodium Azide/pharmacology; Time Factors; Ventricular Function, Left/drug effects

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Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Carnosine / Reperfusion Injury / Histidine Limits: Animals Language: En Journal: J Mol Cell Cardiol Year: 1999 Document type: Article

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