The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors.

Ishii, H; Baffa, R; Numata, S I; Murakumo, Y; Rattan, S; Inoue, H; Mori, M; Fidanza, V; Alder, H; Croce, C M

Ishii, H; Baffa, R; Numata, S I; Murakumo, Y; Rattan, S; Inoue, H; Mori, M; Fidanza, V; Alder, H; Croce, C M.

Affiliation

Ishii H; Kimmel Cancer Institute, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.

Proc Natl Acad Sci U S A ; 96(7): 3928-33, 1999 Mar 30.

Article in En | MEDLINE | ID: mdl-10097140

Subject(s)

Chromosomes, Human, Pair 8; DNA-Binding Proteins/genetics; Genes, Tumor Suppressor; Loss of Heterozygosity; Neoplasms/genetics; Transcription, Genetic; Tumor Suppressor Proteins; Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Breast Neoplasms/genetics; Chromosome Mapping; Cloning, Molecular; DNA-Binding Proteins/biosynthesis; DNA-Binding Proteins/chemistry; Esophageal Neoplasms/genetics; Female; Gene Library; Humans; Leucine Zippers; Male; Molecular Sequence Data; Nerve Tissue Proteins; Ovarian Neoplasms/genetics; Prostatic Neoplasms/genetics; RNA, Messenger/analysis; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Homology, Amino Acid; Testis/metabolism; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / Chromosomes, Human, Pair 8 / Genes, Tumor Suppressor / Loss of Heterozygosity / Tumor Suppressor Proteins / DNA-Binding Proteins / Neoplasms Type of study: Prognostic_studies Limits: Female / Humans / Male Language: En Journal: Proc Natl Acad Sci U S A Year: 1999 Document type: Article

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