Simultaneous determination of NK-104 and its lactone in biological samples by column-switching high-performance liquid chromatography with ultraviolet detection.

Kojima, J; Fujino, H; Yosimura, M; Morikawa, H; Kimata, H

Kojima, J; Fujino, H; Yosimura, M; Morikawa, H; Kimata, H.

Affiliation

Kojima J; Tokyo Research Laboratories, Kowa Company Ltd., Higashimurayama, Japan.

J Chromatogr B Biomed Sci Appl ; 724(1): 173-80, 1999 Mar 05.

Article in En | MEDLINE | ID: mdl-10202970

Subject(s)

Chromatography, High Pressure Liquid/methods; Hydroxymethylglutaryl-CoA Reductase Inhibitors/blood; Lactones/blood; Quinolines/blood; Animals; Dogs; Humans; Hydroxamic Acids/chemistry; Quinolines/chemistry; Rats; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

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Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Chromatography, High Pressure Liquid / Hydroxymethylglutaryl-CoA Reductase Inhibitors / Lactones Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: J Chromatogr B Biomed Sci Appl Year: 1999 Document type: Article

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