Effects of a frequent apolipoprotein E isoform, ApoE4Freiburg (Leu28-->Pro), on lipoproteins and the prevalence of coronary artery disease in whites.

Orth, M; Weng, W; Funke, H; Steinmetz, A; Assmann, G; Nauck, M; Dierkes, J; Ambrosch, A; Weisgraber, K H; Mahley, R W; Wieland, H; Luley, C

Orth, M; Weng, W; Funke, H; Steinmetz, A; Assmann, G; Nauck, M; Dierkes, J; Ambrosch, A; Weisgraber, K H; Mahley, R W; Wieland, H; Luley, C.

Affiliation

Orth M; Institut für Klinische Chemie und Pathobiochemie, Universität Magdeburg, Germany.

Arterioscler Thromb Vasc Biol ; 19(5): 1306-15, 1999 May.

Article in En | MEDLINE | ID: mdl-10323784

Subject(s)

Amino Acid Substitution; Apolipoproteins E/genetics; Coronary Disease/epidemiology; Protein Isoforms/genetics; White People/genetics; Adult; Aged; Alleles; Apolipoprotein E4; Apolipoproteins/blood; Apolipoproteins E/isolation & purification; Blood Protein Electrophoresis; Chylomicrons/blood; Comorbidity; Coronary Disease/blood; Coronary Disease/genetics; Eating; Female; Gene Frequency; Genotype; Germany/epidemiology; Humans; Hyperlipoproteinemias/blood; Hyperlipoproteinemias/epidemiology; Hyperlipoproteinemias/genetics; Isoelectric Focusing; Lipids/blood; Lipoproteins/metabolism; Lipoproteins, HDL/metabolism; Male; Middle Aged; Myocardial Infarction/blood; Myocardial Infarction/epidemiology; Myocardial Infarction/genetics; Odds Ratio; Phenotype; Polymorphism, Restriction Fragment Length; Prevalence; Protein Isoforms/isolation & purification; Receptors, LDL/metabolism; Risk Factors; Triglycerides/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins E / Coronary Disease / Amino Acid Substitution / Protein Isoforms / White People Type of study: Etiology_studies / Prevalence_studies / Risk_factors_studies Country/Region as subject: Europa Language: En Journal: Arterioscler Thromb Vasc Biol Year: 1999 Document type: Article

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