Local intramural heparin delivery during primary angioplasty for acute myocardial infarction: results of the Local PAMI Pilot Study.
Catheter Cardiovasc Interv
; 47(2): 237-42, 1999 Jun.
Article
in En
| MEDLINE
| ID: mdl-10376513
ABSTRACT
The feasibility and safety of local heparin delivery during acute infarct angioplasty was evaluated in a prospective, multicenter, 120-patient series. Angioplasty was performed using standard techniques, after which heparin (4,000 U) was delivered locally; 25% of patients received stents. Procedural success was reported in 98% of patients; 6.7% of patients suffered death, reinfarction, recurrent ischemia, or stroke during the index hospitalization. The 6-month target vessel revascularization rate was 12.5%. Local heparin therapy with provisional stenting in acute myocardial infarction patients is safe, feasible, associated with a low rate of infarct artery revascularization at 6 months, and may potentially eliminate the need for systemic heparin following the procedure.
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Collection:
01-internacional
Health context:
6_ODS3_enfermedades_notrasmisibles
Database:
MEDLINE
Main subject:
Heparin
/
Angioplasty, Balloon, Coronary
/
Fibrinolytic Agents
/
Myocardial Infarction
Type of study:
Clinical_trials
/
Observational_studies
/
Risk_factors_studies
Aspects:
Implementation_research
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Catheter Cardiovasc Interv
Year:
1999
Document type:
Article