Eubacterial tmRNAs: everywhere except the alpha-proteobacteria?
Biochim Biophys Acta
; 1446(1-2): 145-8, 1999 Jul 07.
Article
in En
| MEDLINE
| ID: mdl-10395928
ABSTRACT
Eubacterial tmRNAs mediate, at least in Escherichia coli, recycling of ribosomes stalled at the end of terminatorless mRNAs. A tmRNA-encoded peptide tag is added to abnormal protein products of truncated mRNAs. This tag is a specific signal for proteolysis of the aberrant protein. To obtain further sequence information, PCR was used to amplify more Eubacterial genes for tmRNA. Fifty-eight new tmDNA sequences including from members of nine additional phyla were determined. Remarkably, tmDNA sequences could be amplified from all species tested apart from those in the alpha-Proteobacteria, raising evolutionary implications.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bacteria
/
RNA, Bacterial
Language:
En
Journal:
Biochim Biophys Acta
Year:
1999
Document type:
Article