Direct suppression of TCR-mediated activation of extracellular signal-regulated kinase by leukocyte protein tyrosine phosphatase, a tyrosine-specific phosphatase.

Oh-hora, M; Ogata, M; Mori, Y; Adachi, M; Imai, K; Kosugi, A; Hamaoka, T

Oh-hora, M; Ogata, M; Mori, Y; Adachi, M; Imai, K; Kosugi, A; Hamaoka, T.

Affiliation

Oh-hora M; Biomedical Research Center, Osaka University Medical School, Japan.

J Immunol ; 163(3): 1282-8, 1999 Aug 01.

Article in En | MEDLINE | ID: mdl-10415025

Subject(s)

Calcium-Calmodulin-Dependent Protein Kinases/antagonists & inhibitors; Calcium-Calmodulin-Dependent Protein Kinases/metabolism; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Protein Tyrosine Phosphatases/physiology; Receptors, Antigen, T-Cell/physiology; Tyrosine/metabolism; Cell Line; Enzyme Activation/immunology; Genetic Vectors/metabolism; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Kidney; MAP Kinase Kinase 1; Macromolecular Substances; Phosphorylation; Protein Binding/immunology; Protein Serine-Threonine Kinases/genetics; Protein Serine-Threonine Kinases/metabolism; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases/genetics; Protein Tyrosine Phosphatases, Non-Receptor; Protein-Tyrosine Kinases/genetics; Protein-Tyrosine Kinases/metabolism; Recombinant Fusion Proteins/biosynthesis; Recombinant Fusion Proteins/metabolism; Transfection; p38 Mitogen-Activated Protein Kinases

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Collection: 01-internacional Database: MEDLINE Main subject: Tyrosine / Receptors, Antigen, T-Cell / Protein Tyrosine Phosphatases / Calcium-Calmodulin-Dependent Protein Kinases / Mitogen-Activated Protein Kinase Kinases / Mitogen-Activated Protein Kinases Limits: Humans Language: En Journal: J Immunol Year: 1999 Document type: Article

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