Escape from the acute Wolff-Chaikoff effect is associated with a decrease in thyroid sodium/iodide symporter messenger ribonucleic acid and protein.

Eng, P H; Cardona, G R; Fang, S L; Previti, M; Alex, S; Carrasco, N; Chin, W W; Braverman, L E

Eng, P H; Cardona, G R; Fang, S L; Previti, M; Alex, S; Carrasco, N; Chin, W W; Braverman, L E.

Affiliation

Eng PH; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA. eng@rascal.med.harvard.edu

Endocrinology ; 140(8): 3404-10, 1999 Aug.

Article in En | MEDLINE | ID: mdl-10433193

Subject(s)

Carrier Proteins/genetics; Gene Expression Regulation; Iodides/metabolism; Iodides/pharmacology; Iodine/metabolism; Membrane Proteins/genetics; Symporters; Thyroid Gland/metabolism; Animals; Gene Expression Regulation/drug effects; Iodide Peroxidase/genetics; Male; Peptidylprolyl Isomerase/genetics; Protein Biosynthesis; RNA, Messenger/genetics; Rats; Rats, Sprague-Dawley; Sodium Iodide/administration & dosage; Thyroglobulin/genetics; Thyroid Gland/drug effects; Transcription, Genetic; Water Supply

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Collection: 01-internacional Health context: 2_ODS3 Database: MEDLINE Main subject: Thyroid Gland / Carrier Proteins / Gene Expression Regulation / Symporters / Iodides / Iodine / Membrane Proteins Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Endocrinology Year: 1999 Document type: Article

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