A cell cycle alteration precedes apoptosis of granule cell precursors in the weaver mouse cerebellum.

Migheli, A; Piva, R; Casolino, S; Atzori, C; Dlouhy, S R; Ghetti, B

Migheli, A; Piva, R; Casolino, S; Atzori, C; Dlouhy, S R; Ghetti, B.

Affiliation

Migheli A; Department of Neuroscience, Laboratory of Neuropathology, University of Turin, Italy.

Am J Pathol ; 155(2): 365-73, 1999 Aug.

Article in En | MEDLINE | ID: mdl-10433930

Subject(s)

Apoptosis; Cell Cycle Proteins; Cell Cycle; Cerebellum/metabolism; Cerebellum/physiology; Cyclin A/metabolism; Cyclin-Dependent Kinases/metabolism; Cyclins/metabolism; Mice, Neurologic Mutants; Microtubule-Associated Proteins/metabolism; Potassium Channels, Inwardly Rectifying; Proliferating Cell Nuclear Antigen/analysis; Proliferating Cell Nuclear Antigen/metabolism; Proto-Oncogene Proteins; Tumor Suppressor Proteins; Animals; Cyclin A/analysis; Cyclin D; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases/analysis; Cyclin-Dependent Kinases/antagonists & inhibitors; Cyclins/analysis; DNA Damage; DNA Fragmentation; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Genotype; Humans; Immunohistochemistry; In Situ Hybridization; Ion Channels/physiology; Mice; Microtubule-Associated Proteins/analysis; Mitosis; Mitotic Index; Potassium Channels/metabolism; Substantia Nigra/anatomy & histology; Substantia Nigra/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Cycle / Cerebellum / Proto-Oncogene Proteins / Apoptosis / Cyclins / Proliferating Cell Nuclear Antigen / Cyclin-Dependent Kinases / Cell Cycle Proteins / Cyclin A / Potassium Channels, Inwardly Rectifying Limits: Animals / Humans Language: En Journal: Am J Pathol Year: 1999 Document type: Article

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