Single-bolus tenecteplase compared with front-loaded alteplase in acute myocardial infarction: the ASSENT-2 double-blind randomised trial.

Van De Werf, F; Adgey, J; Ardissino, D; Armstrong, P W; Aylward, P; Barbash, G; Betriu, A; Binbrek, A S; Califf, R; Diaz, R; Fanebust, R; Fox, K; Granger, C; Heikkilä, J; Husted, S; Jansky, P; Langer, A; Lupi, E; Maseri, A; Meyer, J; Mlczoch, J; Mocceti, D; Myburgh, D; Oto, A; Paolasso, E; Pehrsson, K; Seabra-Gomes, R; Soares-Piegas, L; Sùgrue, D; Tendera, M; Topol, E; Toutouzas, P; Vahanian, A; Verheugt, F; Wallentin, L; White, H

Van De Werf, F; Adgey, J; Ardissino, D; Armstrong, P W; Aylward, P; Barbash, G; Betriu, A; Binbrek, A S; Califf, R; Diaz, R; Fanebust, R; Fox, K; Granger, C; Heikkilä, J; Husted, S; Jansky, P; Langer, A; Lupi, E; Maseri, A; Meyer, J; Mlczoch, J; Mocceti, D; Myburgh, D; Oto, A; Paolasso, E; Pehrsson, K; Seabra-Gomes, R; Soares-Piegas, L; Sùgrue, D; Tendera, M; Topol, E; Toutouzas, P; Vahanian, A; Verheugt, F; Wallentin, L; White, H.

Lancet ; 354(9180): 716-22, 1999 Aug 28.

Article in En | MEDLINE | ID: mdl-10475182

Subject(s)

Fibrinolytic Agents/administration & dosage; Myocardial Infarction/drug therapy; Thrombolytic Therapy; Tissue Plasminogen Activator/administration & dosage; Aged; Double-Blind Method; Female; Fibrinolytic Agents/adverse effects; Humans; Male; Middle Aged; Myocardial Infarction/mortality; Survival Rate; Tenecteplase; Tissue Plasminogen Activator/adverse effects; Treatment Outcome

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Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Thrombolytic Therapy / Tissue Plasminogen Activator / Fibrinolytic Agents / Myocardial Infarction Type of study: Clinical_trials / Etiology_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Lancet Year: 1999 Document type: Article

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