Valine 108, a chain-folding initiation site-belonging residue, crucial for the ribonuclease A stability.

Coll, M G; Protasevich, I I; Torrent, J; Ribó, M; Lobachov, V M; Makarov, A A; Vilanova, M

Coll, M G; Protasevich, I I; Torrent, J; Ribó, M; Lobachov, V M; Makarov, A A; Vilanova, M.

Affiliation

Coll MG; Laboratori d'Enginyeria de Proteïnes, Departament de Biologia, Facultat de Ciències, Universitat de Girona, Campus Montilivi, Girona, 17071, Spain.

Biochem Biophys Res Commun ; 265(2): 356-60, 1999 Nov 19.

Article in En | MEDLINE | ID: mdl-10558871

Subject(s)

Ribonuclease, Pancreatic/chemistry; Animals; Calorimetry, Differential Scanning; Cattle; Circular Dichroism; Enzyme Stability; Escherichia coli/genetics; In Vitro Techniques; Models, Molecular; Mutagenesis, Site-Directed; Pancreas/enzymology; Protein Folding; Recombinant Proteins/chemistry; Recombinant Proteins/genetics; Recombinant Proteins/metabolism; Ribonuclease, Pancreatic/genetics; Ribonuclease, Pancreatic/metabolism; Thermodynamics; Valine/chemistry

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Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Ribonuclease, Pancreatic Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 1999 Document type: Article

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