Simplified production of a recombinant human angiostatin derivative that suppresses intracerebral glial tumor growth.

Meneses, P I; Abrey, L E; Hajjar, K A; Gultekin, S H; Duvoisin, R M; Berns, K I; Rosenfeld, M R

Meneses, P I; Abrey, L E; Hajjar, K A; Gultekin, S H; Duvoisin, R M; Berns, K I; Rosenfeld, M R.

Affiliation

Meneses PI; Department of Neurosciences, Weill Medical College of Cornell University, New York, New York 10021, USA.

Clin Cancer Res ; 5(11): 3689-94, 1999 Nov.

Article in En | MEDLINE | ID: mdl-10589788

Subject(s)

Brain Neoplasms/drug therapy; Endothelium, Vascular/cytology; Glioma/drug therapy; Neovascularization, Pathologic/prevention & control; Peptide Fragments/therapeutic use; Plasminogen/therapeutic use; Animals; Brain Neoplasms/blood supply; Brain Neoplasms/pathology; Cell Division/drug effects; Cell Line; Cells, Cultured; Cloning, Molecular; Endothelium, Vascular/drug effects; Female; Glioma/blood supply; Glioma/pathology; Humans; Microcirculation/drug effects; Microcirculation/pathology; Peptide Fragments/genetics; Peptide Fragments/toxicity; Plasminogen/genetics; Plasminogen/toxicity; Rats; Rats, Inbred F344; Recombinant Proteins/therapeutic use; Recombinant Proteins/toxicity; Transfection; Umbilical Veins

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Plasminogen / Brain Neoplasms / Endothelium, Vascular / Glioma / Neovascularization, Pathologic Limits: Animals / Female / Humans Language: En Journal: Clin Cancer Res Year: 1999 Document type: Article

Search on Google

XML

PubMed Links