[Cellular neurothekeoma, a rare cutaneous tumor. Anatomo-clinical and immunohistochemical study of 2 cases]. / Le neurothécome cellulaire, une tumeur cutanée rare. Etude anatomo-clinique et immunohistochimique de deux observations.
Ann Pathol
; 20(3): 225-7, 2000 May.
Article
in Fr
| MEDLINE
| ID: mdl-10891717
ABSTRACT
Cellular neurothekeoma is an unusual cutaneous tumor described in 1986. We report two new cases in 14-year-old girls. Both tumors measured less than one centimeter and were located on the forearm and the shoulder. They had a plexiform architecture and were developed in the dermis and the dermo-hypodermic junction. Spindle and epithelioid tumor cells were immunoreactive for vimentin, NKI-C3, NSE, CD68 and smooth muscle actin. There was no recurrence 2 and 7 months after the operation. Cellular neurothekeoma is a benign tumor. Its histogenesis is still unknown. Histological and immunohistochemical features, with positivity of the tumor cells for NKI-C3, a non specific melanocytic marker, and negativity for S-100 protein and HMB-45, allow to differentiate cellular neurothekeoma from myxoid neurothekeoma and melanocytic tumors.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Skin Neoplasms
/
Neurothekeoma
Limits:
Adolescent
/
Female
/
Humans
Language:
Fr
Journal:
Ann Pathol
Year:
2000
Document type:
Article