Lack of interaction between citalopram and the CYP3A4 substrate triazolam.

Nolting, A; Abramowitz, W

Nolting, A; Abramowitz, W.

Affiliation

Nolting A; Department of Pharmacokinetics, Forest Laboratories, Inc., New York, New York 10022, USA.

Pharmacotherapy ; 20(7): 750-5, 2000 Jul.

Article in En | MEDLINE | ID: mdl-10907965

Subject(s)

Antidepressive Agents/adverse effects; Citalopram/adverse effects; Cytochrome P-450 Enzyme System/metabolism; Hypnotics and Sedatives/pharmacokinetics; Mixed Function Oxygenases/metabolism; Triazolam/pharmacokinetics; Adult; Area Under Curve; Cytochrome P-450 CYP3A; Drug Interactions; Female; Humans; Hypnotics and Sedatives/blood; Male; Triazolam/blood

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Collection: 01-internacional Database: MEDLINE Main subject: Triazolam / Citalopram / Cytochrome P-450 Enzyme System / Mixed Function Oxygenases / Hypnotics and Sedatives / Antidepressive Agents Type of study: Prognostic_studies Limits: Adult / Female / Humans / Male Language: En Journal: Pharmacotherapy Year: 2000 Document type: Article

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