GPIIb-IIIa antagonist-induced reduction in platelet surface factor V/Va binding and phosphatidylserine expression in whole blood.

Furman, M I; Krueger, L A; Frelinger, A L; Barnard, M R; Mascelli, M A; Nakada, M T; Michelson, A D

Furman, M I; Krueger, L A; Frelinger, A L; Barnard, M R; Mascelli, M A; Nakada, M T; Michelson, A D.

Affiliation

Furman MI; Center for Platelet Function Studies, University of Massachusetts Medical School, Worcester, PA 01655, USA. Furman@platelets.org

Thromb Haemost ; 84(3): 492-8, 2000 Sep.

Article in En | MEDLINE | ID: mdl-11019977

Subject(s)

Factor V/metabolism; Phosphatidylserines/blood; Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors; Tyrosine/analogs & derivatives; Abciximab; Antibodies, Monoclonal/pharmacology; Blood Platelets/metabolism; Collagen/pharmacology; Dose-Response Relationship, Drug; Eptifibatide; Flow Cytometry; Humans; Immunoglobulin Fab Fragments/pharmacology; Infant, Newborn; Membrane Proteins/metabolism; Peptides/pharmacology; Protein Binding; Thrombasthenia/blood; Thrombin/antagonists & inhibitors; Thrombin/pharmacology; Tirofiban; Tyrosine/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Phosphatidylserines / Tyrosine / Factor V / Platelet Glycoprotein GPIIb-IIIa Complex Limits: Humans / Newborn Language: En Journal: Thromb Haemost Year: 2000 Document type: Article

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