Human apolipoprotein E7:lysine mutations in the carboxy-terminal domain are directly responsible for preferential binding to very low density lipoproteins.

Dong, J; Balestra, M E; Newhouse, Y M; Weisgraber, K H

Dong, J; Balestra, M E; Newhouse, Y M; Weisgraber, K H.

Affiliation

Dong J; Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94141, USA.

J Lipid Res ; 41(11): 1783-9, 2000 Nov.

Article in En | MEDLINE | ID: mdl-11060347

Subject(s)

Apolipoproteins E/genetics; Apolipoproteins E/metabolism; Lipoproteins, VLDL/metabolism; Lysine/genetics; Mutation; Apolipoprotein E3; Dimyristoylphosphatidylcholine/metabolism; Emulsions; Heparin/metabolism; Humans; Microscopy, Electron; Mutagenesis, Site-Directed; Particle Size; Receptors, LDL/metabolism; Recombinant Proteins/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins E / Lipoproteins, VLDL / Lysine / Mutation Limits: Humans Language: En Journal: J Lipid Res Year: 2000 Document type: Article

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