Damage of the kinesin heavy chain gene contributes to the antagonism of cisplatin and paclitaxel.

Efferth, T; Fabry, U; Osieka, R

Efferth, T; Fabry, U; Osieka, R.

Affiliation

Efferth T; Department for Internal Medicine IV, University Hospital, RWTH Aachen, Germany. tseffert@viro.med.uni-erlangen.de

Anticancer Res ; 20(5A): 3211-9, 2000.

Article in En | MEDLINE | ID: mdl-11062745

Subject(s)

Antineoplastic Agents, Phytogenic/metabolism; Antineoplastic Agents/metabolism; Cisplatin/metabolism; Kinesins/genetics; Paclitaxel/metabolism; Antineoplastic Agents/pharmacology; Antineoplastic Agents, Phytogenic/pharmacology; Apoptosis/drug effects; Cell Division/drug effects; Cisplatin/pharmacology; DNA Damage/drug effects; Drug Antagonism; Humans; K562 Cells; Kinesins/immunology; Kinesins/metabolism; Oligonucleotides, Antisense; Paclitaxel/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Cisplatin / Kinesins / Paclitaxel / Antineoplastic Agents / Antineoplastic Agents, Phytogenic Limits: Humans Language: En Journal: Anticancer Res Year: 2000 Document type: Article

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