Steady-state pharmacokinetics of (R)- and (S)-methadone in methadone maintenance patients.

Foster, D J; Somogyi, A A; Dyer, K R; White, J M; Bochner, F

Foster, D J; Somogyi, A A; Dyer, K R; White, J M; Bochner, F.

Affiliation

Foster DJ; Department of Cinical and Experimental Pharmacology, University of Adelaide, Adelaide, 5005, Australia. david.foster@adelaide.edu.au

Br J Clin Pharmacol ; 50(5): 427-40, 2000 Nov.

Article in En | MEDLINE | ID: mdl-11069437

Subject(s)

Methadone/pharmacokinetics; Narcotics/pharmacokinetics; Adult; Area Under Curve; Female; Humans; Individuality; Kidney/metabolism; Linear Models; Male; Methadone/blood; Methadone/urine; Middle Aged; Narcotics/blood; Narcotics/urine; Orosomucoid/metabolism; Protein Binding; Pyrrolidines/blood; Pyrrolidines/urine; Stereoisomerism; Substance-Related Disorders/blood; Substance-Related Disorders/rehabilitation; Substance-Related Disorders/urine; Substrate Specificity

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Full text: 1 Collection: 01-internacional Health context: 2_ODS3 / 8_ODS3_consumo_sustancias_psicoactivas Database: MEDLINE Main subject: Methadone / Narcotics Type of study: Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Br J Clin Pharmacol Year: 2000 Document type: Article

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