A potential RNA drug target in the hepatitis C virus internal ribosomal entry site.

Klinck, R; Westhof, E; Walker, S; Afshar, M; Collier, A; Aboul-Ela, F

Klinck, R; Westhof, E; Walker, S; Afshar, M; Collier, A; Aboul-Ela, F.

Affiliation

Klinck R; RiboTargets Ltd., Abington, Cambridge, United Kingdom.

RNA ; 6(10): 1423-31, 2000 Oct.

Article in En | MEDLINE | ID: mdl-11073218

Subject(s)

Drug Design; Fungal Proteins; Hepacivirus/genetics; Nucleic Acid Conformation; RNA, Viral/chemistry; RNA, Viral/metabolism; Regulatory Sequences, Nucleic Acid/genetics; Ribosomes/metabolism; Base Pairing; Base Sequence; Computational Biology; Endoribonucleases/metabolism; Genetic Engineering; Models, Molecular; Molecular Sequence Data; Mutation; Nuclear Magnetic Resonance, Biomolecular; Protein Biosynthesis; RNA, Messenger/chemistry; RNA, Messenger/genetics; RNA, Messenger/metabolism; RNA, Viral/genetics; Reproducibility of Results; Ricin/metabolism; Structure-Activity Relationship; Substrate Specificity

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Full text: 1 Collection: 01-internacional Health context: 2_ODS3 Database: MEDLINE Main subject: Ribosomes / RNA, Viral / Fungal Proteins / Drug Design / Regulatory Sequences, Nucleic Acid / Hepacivirus / Nucleic Acid Conformation Type of study: Prognostic_studies Language: En Journal: RNA Year: 2000 Document type: Article

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