Comparison of immunotoxins bearing a single saporin molecule with multiple toxin conjugates.

Flavell, D J; Flavell, S U

Flavell, D J; Flavell, S U.

Affiliation

Flavell DJ; Division of Cancer Sciences, Simon Flavell Leukemia Research Laboratory, University of Southampton, Southampton General Hospital, Hampshire, UK.

Methods Mol Biol ; 166: 87-100, 2001.

Article in En | MEDLINE | ID: mdl-11217378

Subject(s)

Immunotoxins/chemistry; N-Glycosyl Hydrolases; Plant Proteins/chemistry; Ribosomes/drug effects; Animals; Chromatography, Ion Exchange; Humans; Hydrogen-Ion Concentration; Immunoglobulin G/chemistry; Immunoglobulin G/pharmacology; Immunotoxins/isolation & purification; Immunotoxins/pharmacology; Immunotoxins/therapeutic use; Lymphoma/drug therapy; Mice; Mice, SCID; Plant Proteins/isolation & purification; Plant Proteins/pharmacology; Plant Proteins/therapeutic use; Protein Biosynthesis/drug effects; Ribosome Inactivating Proteins, Type 1; Saporins; Xenograft Model Antitumor Assays

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Collection: 01-internacional Database: MEDLINE Main subject: Plant Proteins / Ribosomes / Immunotoxins / N-Glycosyl Hydrolases Limits: Animals / Humans Language: En Journal: Methods Mol Biol Year: 2001 Document type: Article

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