Tissue factor-mediated endocytosis, recycling, and degradation of factor VIIa by a clathrin-independent mechanism not requiring the cytoplasmic domain of tissue factor.

Hansen, C B; Pyke, C; Petersen, L C; Rao, L V

Hansen, C B; Pyke, C; Petersen, L C; Rao, L V.

Affiliation

Hansen CB; Department of Tissue Factor/Factor VIIa (TF/VIIa) Research, Health Care Discovery, Novo Nordisk A/S, Maalov, Denmark.

Blood ; 97(6): 1712-20, 2001 Mar 15.

Article in En | MEDLINE | ID: mdl-11238112

Subject(s)

Endocytosis/drug effects; Factor VIIa/physiology; Thromboplastin/pharmacology; Animals; Cell Line; Clathrin; Cricetinae; Endocytosis/physiology; Factor VIIa/drug effects; Factor VIIa/pharmacokinetics; Factor Xa/pharmacology; Iodine Radioisotopes; Lipoproteins/pharmacology; Microscopy, Fluorescence; Protein Binding; Thromboplastin/genetics; Thromboplastin/metabolism; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Thromboplastin / Factor VIIa / Endocytosis Limits: Animals Language: En Journal: Blood Year: 2001 Document type: Article

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