Effect of N-acetyl-seryl-aspartyl-lysyl-proline on DNA and collagen synthesis in rat cardiac fibroblasts.

Rhaleb, N E; Peng, H; Harding, P; Tayeh, M; LaPointe, M C; Carretero, O A

Rhaleb, N E; Peng, H; Harding, P; Tayeh, M; LaPointe, M C; Carretero, O A.

Affiliation

Rhaleb NE; Hypertension and Vascular Research Division, Henry Ford Hospital, Detroit, MI 48202-2689, USA. nrhaleb1@hfhs.org

Hypertension ; 37(3): 827-32, 2001 Mar.

Article in En | MEDLINE | ID: mdl-11244003

Subject(s)

Angiotensin II/physiology; Collagen/biosynthesis; Myocardium/metabolism; Oligopeptides/pharmacology; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors/metabolism; Angiotensin-Converting Enzyme Inhibitors/therapeutic use; Animals; Cell Division/drug effects; Cells, Cultured; DNA/biosynthesis; Dose-Response Relationship, Drug; Endothelin-1/antagonists & inhibitors; Enzyme Activation/drug effects; Enzyme Inhibitors/pharmacology; Fibrosis/drug therapy; Gene Expression Regulation/drug effects; Humans; Hypertension/drug therapy; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases/antagonists & inhibitors; Mitogen-Activated Protein Kinases/metabolism; Oligopeptides/blood; Oligopeptides/metabolism; Peptidyl-Dipeptidase A/metabolism; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin/metabolism; Renin-Angiotensin System

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Angiotensin II / Collagen / Myocardium Limits: Animals / Humans Language: En Journal: Hypertension Year: 2001 Document type: Article

Fulltext

XML

PubMed Links

Search on Google