Determination of UDP-glucuronosyltransferase UGT1A6 activity in human and rat liver microsomes by HPLC with UV detection.

Hanioka, N; Jinno, H; Tanaka-Kagawa, T; Nishimura, T; Ando, M

Hanioka, N; Jinno, H; Tanaka-Kagawa, T; Nishimura, T; Ando, M.

Affiliation

Hanioka N; Division of Environmental Chemistry, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan. hanioka@nihs.go.jp

J Pharm Biomed Anal ; 25(1): 65-75, 2001 Apr.

Article in En | MEDLINE | ID: mdl-11274859

Subject(s)

Chromatography, High Pressure Liquid/methods; Glucuronosyltransferase/analysis; Microsomes, Liver/enzymology; Animals; Calibration; Enzyme Induction; Enzyme Stability; Glucuronates/chemistry; Humans; Kinetics; Male; Nitrophenols/metabolism; Quality Control; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrophotometry, Ultraviolet/methods

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PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Microsomes, Liver / Chromatography, High Pressure Liquid / Glucuronosyltransferase Type of study: Diagnostic_studies Limits: Animals / Humans / Male Language: En Journal: J Pharm Biomed Anal Year: 2001 Document type: Article

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