Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors.

Crispino, J D; Lodish, M B; Thurberg, B L; Litovsky, S H; Collins, T; Molkentin, J D; Orkin, S H

Crispino, J D; Lodish, M B; Thurberg, B L; Litovsky, S H; Collins, T; Molkentin, J D; Orkin, S H.

Affiliation

Crispino JD; Division of Hematology and Oncology, Children's Hospital, Boston, Massachusetts 02115, USA.

Genes Dev ; 15(7): 839-44, 2001 Apr 01.

Article in En | MEDLINE | ID: mdl-11297508

Subject(s)

Coronary Vessel Anomalies/genetics; Coronary Vessels/embryology; DNA-Binding Proteins/physiology; Fetal Heart/growth & development; Heart Defects, Congenital/genetics; Transcription Factors/physiology; Amino Acid Sequence; Amino Acid Substitution; Animals; Basic Helix-Loop-Helix Transcription Factors; Coronary Vessel Anomalies/embryology; DNA-Binding Proteins/biosynthesis; DNA-Binding Proteins/chemistry; DNA-Binding Proteins/deficiency; DNA-Binding Proteins/genetics; Embryonic and Fetal Development/genetics; Erythroid-Specific DNA-Binding Factors; Fetal Heart/pathology; GATA4 Transcription Factor; Genes, Lethal; Gestational Age; Heart Defects, Congenital/embryology; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Molecular; Molecular Sequence Data; Morphogenesis/genetics; Mutagenesis, Site-Directed; Protein Conformation; Transcription Factors/biosynthesis; Transcription Factors/chemistry; Transcription Factors/deficiency; Transcription Factors/genetics; Transcription, Genetic; Valine/chemistry; Zebrafish Proteins

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Coronary Vessel Anomalies / Coronary Vessels / DNA-Binding Proteins / Fetal Heart / Heart Defects, Congenital Type of study: Prognostic_studies Language: En Journal: Genes Dev Year: 2001 Document type: Article

Fulltext

XML

PubMed Links

Search on Google