Nitric oxide induces metallothionein (MT) gene expression apparently by displacing zinc bound to MT.

Katakai, K; Liu, J; Nakajima, K; Keefer, L K; Waalkes, M P

Katakai, K; Liu, J; Nakajima, K; Keefer, L K; Waalkes, M P.

Affiliation

Katakai K; Laboratory of Comparative Carcinogenesis, NCI at NIEHS, Research, Mail Drop F0-09, 111 Alexander Drive, 27709, Research Triangle Park, NC, USA.

Toxicol Lett ; 119(2): 103-8, 2001 Feb 28.

Article in En | MEDLINE | ID: mdl-11311571

Subject(s)

Gene Expression/drug effects; Metallothionein/genetics; Nitric Oxide Donors/pharmacology; Nitric Oxide/pharmacology; Triazenes/pharmacology; Zinc/metabolism; Animals; Humans; Metallothionein/metabolism; RNA, Messenger/drug effects; RNA, Messenger/metabolism; Rats; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Triazenes / Zinc / Gene Expression / Nitric Oxide Donors / Metallothionein / Nitric Oxide Limits: Animals / Humans Language: En Journal: Toxicol Lett Year: 2001 Document type: Article

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