P2y(12), a new platelet ADP receptor, target of clopidogrel.

Savi, P; Labouret, C; Delesque, N; Guette, F; Lupker, J; Herbert, J M

Savi, P; Labouret, C; Delesque, N; Guette, F; Lupker, J; Herbert, J M.

Affiliation

Savi P; Cardiovascular/Thrombosis Research Department, Sanofi-Synthélabo, 195 Route d'Espagne, Toulouse, 31036, France.

Biochem Biophys Res Commun ; 283(2): 379-83, 2001 May 04.

Article in En | MEDLINE | ID: mdl-11327712

Subject(s)

Blood Platelets/drug effects; Blood Platelets/metabolism; Receptors, Purinergic P2/blood; Receptors, Purinergic P2/drug effects; Ticlopidine/analogs & derivatives; Ticlopidine/pharmacology; Adenosine Diphosphate/analogs & derivatives; Adenosine Diphosphate/metabolism; Adenylyl Cyclases/metabolism; Animals; CHO Cells; Clopidogrel; Cricetinae; Down-Regulation; Humans; Kinetics; Receptors, Purinergic P2/genetics; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Blood Platelets / Ticlopidine / Receptors, Purinergic P2 Limits: Animals / Humans Language: En Journal: Biochem Biophys Res Commun Year: 2001 Document type: Article

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