Studies on the binding of 3H-SR121566, an inhibitor of Gp IIb-IIIa activation.

Savi, P; Zamboni, G; Rescanières, O; Herbert, J M

Savi, P; Zamboni, G; Rescanières, O; Herbert, J M.

Affiliation

Savi P; Cardiovascular/Thrombosis Research Dept, Sanofi-Synthélabo, Toulouse, France.

Thromb Haemost ; 85(4): 702-9, 2001 Apr.

Article in En | MEDLINE | ID: mdl-11341508

Subject(s)

Platelet Activation/drug effects; Platelet Aggregation Inhibitors/metabolism; Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors; Abciximab; Antibodies, Monoclonal/pharmacology; Benzylamines; Binding Sites; Binding, Competitive; Blood Cells/drug effects; Blood Cells/metabolism; Cell Line/drug effects; Cell Line/metabolism; Endothelium, Vascular/drug effects; Endothelium, Vascular/metabolism; Fibrinogen/metabolism; Flow Cytometry; Humans; Immunoglobulin Fab Fragments/pharmacology; Oligopeptides/chemical synthesis; Oligopeptides/metabolism; Organ Specificity; Piperidines; Platelet Aggregation Inhibitors/pharmacology; Protein Conformation/drug effects; Proteins/pharmacology; Receptors, Thrombin; Thiazoles

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Collection: 01-internacional Database: MEDLINE Main subject: Platelet Aggregation Inhibitors / Platelet Activation / Platelet Glycoprotein GPIIb-IIIa Complex Limits: Humans Language: En Journal: Thromb Haemost Year: 2001 Document type: Article

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