Coumarins isolated from Angelica gigas inhibit acetylcholinesterase: structure-activity relationships.
J Nat Prod
; 64(5): 683-5, 2001 May.
Article
in En
| MEDLINE
| ID: mdl-11374978
ABSTRACT
Acetylcholinesterase (AChE) inhibitory activity-guided fractionation of Angelica gigas led to isolation and identification of a new coumarin, peucedanone (12), and isolation of 11 known coumarins. Among them, decursinol (1) represented the highest inhibitory activity toward AChE in vitro. The correlation of the inhibitory activities of the coumarins toward AChE with their chemical structures was studied.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Plants, Medicinal
/
Cholinesterase Inhibitors
/
Coumarins
Country/Region as subject:
Asia
Language:
En
Journal:
J Nat Prod
Year:
2001
Document type:
Article