The adapter protein apoptotic protease-activating factor-1 (Apaf-1) is proteolytically processed during apoptosis.

Lauber, K; Appel, H A; Schlosser, S F; Gregor, M; Schulze-Osthoff, K; Wesselborg, S

Lauber, K; Appel, H A; Schlosser, S F; Gregor, M; Schulze-Osthoff, K; Wesselborg, S.

Affiliation

Lauber K; Department of Internal Medicine I, University of Tübingen, D-72076 Tübingen, Germany.

J Biol Chem ; 276(32): 29772-81, 2001 Aug 10.

Article in En | MEDLINE | ID: mdl-11387322

Subject(s)

Apoptosis; Proteins/chemistry; Proteins/physiology; Adenosine Triphosphate/metabolism; Apoptotic Protease-Activating Factor 1; Caspase 3; Caspase 6; Caspase 8; Caspase 9; Caspases/metabolism; Cytochrome c Group/metabolism; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors/pharmacology; Etoposide/pharmacology; HeLa Cells; Humans; Immunoblotting; Jurkat Cells; Mitomycin/pharmacology; Models, Biological; Mutation; Nucleic Acid Synthesis Inhibitors/pharmacology; Protein Binding; Protein Structure, Tertiary; Proteins/metabolism; Repetitive Sequences, Amino Acid; Staurosporine/pharmacology; Time Factors; fas Receptor/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Proteins / Apoptosis Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2001 Document type: Article

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