Tyrosine 36 plays a critical role in the interaction of the AB loop of tissue inhibitor of metalloproteinases-2 with matrix metalloproteinase-14.

Williamson, R A; Hutton, M; Vogt, G; Rapti, M; Knäuper, V; Carr, M D; Murphy, G

Williamson, R A; Hutton, M; Vogt, G; Rapti, M; Knäuper, V; Carr, M D; Murphy, G.

Affiliation

Williamson RA; School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, United Kingdom.

J Biol Chem ; 276(35): 32966-70, 2001 Aug 31.

Article in En | MEDLINE | ID: mdl-11390386

Subject(s)

Metalloendopeptidases/chemistry; Metalloendopeptidases/metabolism; Tissue Inhibitor of Metalloproteinase-2/chemistry; Tissue Inhibitor of Metalloproteinase-2/metabolism; Tyrosine; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Crystallography, X-Ray; Humans; Kinetics; Matrix Metalloproteinases, Membrane-Associated; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Protein Structure, Secondary; Recombinant Proteins/chemistry; Recombinant Proteins/metabolism; Sequence Alignment; Sequence Deletion; Sequence Homology, Amino Acid

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Tyrosine / Metalloendopeptidases / Tissue Inhibitor of Metalloproteinase-2 Limits: Humans Language: En Journal: J Biol Chem Year: 2001 Document type: Article

Search on Google

XML

PubMed Links