Downregulation of the ERK 1 and 2 mitogen activated protein kinases using antisense oligonucleotides inhibits proliferation of porcine vascular smooth muscle cells.

Fisher, M; Liu, B; Glennon, P E; Southgate, K M; Sale, E M; Sale, G J; Lewis, M J; Groves, P H

Fisher, M; Liu, B; Glennon, P E; Southgate, K M; Sale, E M; Sale, G J; Lewis, M J; Groves, P H.

Affiliation

Fisher M; Cardiovascular Sciences Research Group, Wales Heart Research Institute, University of Wales College of Medicine, Heath Park, CF4 4XN, Cardiff, UK. fisherm@cardiff.ac.uk

Atherosclerosis ; 156(2): 289-95, 2001 Jun.

Article in En | MEDLINE | ID: mdl-11395024

Subject(s)

Cell Division/drug effects; Mitogen-Activated Protein Kinase 1/drug effects; Mitogen-Activated Protein Kinase 1/metabolism; Mitogen-Activated Protein Kinases/drug effects; Mitogen-Activated Protein Kinases/metabolism; Muscle, Smooth, Vascular/cytology; Muscle, Smooth, Vascular/enzymology; Oligonucleotides, Antisense/pharmacology; Analysis of Variance; Animals; Blotting, Western; Cell Division/physiology; Cells, Cultured; Down-Regulation; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 3; Probability; Sensitivity and Specificity; Swine

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Collection: 01-internacional Database: MEDLINE Main subject: Cell Division / Oligonucleotides, Antisense / Mitogen-Activated Protein Kinase 1 / Mitogen-Activated Protein Kinases / Muscle, Smooth, Vascular Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Atherosclerosis Year: 2001 Document type: Article

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