Role of Gab proteins in phosphatidylinositol 3-kinase activation by thrombopoietin (Tpo).

Bouscary, D; Lecoq-Lafon, C; Chrétien, S; Zompi, S; Fichelson, S; Muller, O; Porteu, F; Dusanter-Fourt, I; Gisselbrecht, S; Mayeux, P; Lacombe, C

Bouscary, D; Lecoq-Lafon, C; Chrétien, S; Zompi, S; Fichelson, S; Muller, O; Porteu, F; Dusanter-Fourt, I; Gisselbrecht, S; Mayeux, P; Lacombe, C.

Affiliation

Bouscary D; Institut Cochin de Génétique Moléculaire (ICGM), Institut National de la Santé et de la Recherche Médicale (INSERM U363), Université René Descartes, France.

Oncogene ; 20(18): 2197-204, 2001 Apr 26.

Article in En | MEDLINE | ID: mdl-11402314

Subject(s)

Phosphatidylinositol 3-Kinases/metabolism; Phosphoproteins/physiology; Protein Serine-Threonine Kinases; Thrombopoietin/pharmacology; Adaptor Proteins, Signal Transducing; Animals; Cell Division/drug effects; Cell Division/physiology; Enzyme Activation/drug effects; Fetal Blood/cytology; Hematopoietic Stem Cells/cytology; Hematopoietic Stem Cells/drug effects; Hematopoietic Stem Cells/metabolism; Humans; Megakaryocytes/cytology; Megakaryocytes/drug effects; Megakaryocytes/metabolism; Mice; Phosphoproteins/metabolism; Phosphorylation; Proto-Oncogene Proteins/metabolism; Proto-Oncogene Proteins c-akt; Rabbits; Recombinant Proteins/pharmacology; Signal Transduction/drug effects; Signal Transduction/physiology; Thrombopoietin/genetics; Tyrosine/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Phosphoproteins / Thrombopoietin / Protein Serine-Threonine Kinases / Phosphatidylinositol 3-Kinases Limits: Animals / Humans Language: En Journal: Oncogene Year: 2001 Document type: Article

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