Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.

van den Elsen, J M; Kuntz, D A; Rose, D R

van den Elsen, J M; Kuntz, D A; Rose, D R.

Affiliation

van den Elsen JM; Ontario Cancer Institute and Department of Medical Biophysics, University of Toronto, 610 University Avenue, Toronto, Ontario, Canada.

EMBO J ; 20(12): 3008-17, 2001 Jun 15.

Article in En | MEDLINE | ID: mdl-11406577

Subject(s)

Mannosidases/chemistry; 1-Deoxynojirimycin/pharmacology; Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic/pharmacology; Binding Sites; Catalysis; Cell Division; Cell Line; Crystallography, X-Ray; Drosophila melanogaster/chemistry; Enzyme Inhibitors/pharmacology; Gene Expression; Mannosidases/antagonists & inhibitors; Mannosidases/genetics; Models, Molecular; Molecular Sequence Data; Neoplasm Metastasis; Protein Structure, Secondary; Substrate Specificity; Swainsonine/pharmacology; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mannosidases Limits: Animals Language: En Journal: EMBO J Year: 2001 Document type: Article

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