Apolipoprotein E phenotype and the efficacy of intravenous tissue plasminogen activator in acute ischemic stroke.

Broderick, J; Lu, M; Jackson, C; Pancioli, A; Tilley, B C; Fagan, S C; Kothari, R; Levine, S R; Marler, J R; Lyden, P D; Haley, E C; Brott, T; Grotta, J C

Broderick, J; Lu, M; Jackson, C; Pancioli, A; Tilley, B C; Fagan, S C; Kothari, R; Levine, S R; Marler, J R; Lyden, P D; Haley, E C; Brott, T; Grotta, J C.

Affiliation

Broderick J; Department of Neurology, University of Cincinnati, OH 45267-0525, USA. joseph.broderick@uc.edu

Ann Neurol ; 49(6): 736-44, 2001 Jun.

Article in En | MEDLINE | ID: mdl-11409425

Subject(s)

Apolipoproteins E/genetics; Cerebral Hemorrhage/genetics; Stroke/drug therapy; Stroke/genetics; Tissue Plasminogen Activator/therapeutic use; Aged; Aged, 80 and over; Apolipoprotein E2; Apolipoprotein E4; Apolipoproteins E/blood; Cerebral Hemorrhage/blood; Cerebral Hemorrhage/drug therapy; Cerebral Hemorrhage/pathology; Chi-Square Distribution; Double-Blind Method; Female; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Multicenter Studies as Topic; Odds Ratio; Phenotype; Placebos; Randomized Controlled Trials as Topic; Retrospective Studies; Stroke/blood; Stroke/pathology; Survival Rate; Time Factors; Tissue Plasminogen Activator/blood; Tomography, X-Ray Computed; Treatment Outcome

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Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Apolipoproteins E / Cerebral Hemorrhage / Tissue Plasminogen Activator / Stroke Type of study: Etiology_studies / Observational_studies / Risk_factors_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Ann Neurol Year: 2001 Document type: Article

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