Prolonged inhibition of cholesterol synthesis by atorvastatin inhibits apo B-100 and triglyceride secretion from HepG2 cells.

Funatsu, T; Suzuki, K; Goto, M; Arai, Y; Kakuta, H; Tanaka, H; Yasuda, S; Ida, M; Nishijima, S; Miyata, K

Funatsu, T; Suzuki, K; Goto, M; Arai, Y; Kakuta, H; Tanaka, H; Yasuda, S; Ida, M; Nishijima, S; Miyata, K.

Affiliation

Funatsu T; Pharmacology Laboratory, Institute for Drug Discovery Research, 21 Miyukigaoka, Tsukuba-shi, Ibaraki 3058585, Japan. funatsu@yamanouchi.co.jp

Atherosclerosis ; 157(1): 107-15, 2001 Jul.

Article in En | MEDLINE | ID: mdl-11427209

Subject(s)

Anticholesteremic Agents/pharmacology; Apolipoproteins B/metabolism; Cholesterol/biosynthesis; Heptanoic Acids/pharmacology; Liver/metabolism; Pyrroles/pharmacology; Triglycerides/metabolism; Apolipoprotein B-100; Atorvastatin; Cell Line; Down-Regulation; Humans; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins B / Pyrroles / Triglycerides / Cholesterol / Heptanoic Acids / Liver / Anticholesteremic Agents Limits: Humans Language: En Journal: Atherosclerosis Year: 2001 Document type: Article

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