Members of the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway are present and active in human sperm.

D'Cruz, O J; Vassilev, A O; Uckun, F M

D'Cruz, O J; Vassilev, A O; Uckun, F M.

Affiliation

D'Cruz OJ; Department of Reproductive Biology, Parker Hughes Institute, St. Paul, Minnesota 55113, USA. odcruz@ih.org

Fertil Steril ; 76(2): 258-66, 2001 Aug.

Article in En | MEDLINE | ID: mdl-11476770

Subject(s)

DNA-Binding Proteins/metabolism; Protein-Tyrosine Kinases; Proteins/metabolism; Signal Transduction; Spermatozoa/enzymology; Trans-Activators/metabolism; Trans-Activators/physiology; Blotting, Western; Calcimycin/pharmacology; Calcium/metabolism; Fluorescent Antibody Technique, Indirect; Humans; Interferon-alpha/pharmacology; Interferon-gamma/pharmacology; Interleukin-12/pharmacology; Jurkat Cells; Male; Microscopy, Electron; Phosphorylation; Progesterone/pharmacology; STAT1 Transcription Factor; STAT4 Transcription Factor; Spermatozoa/drug effects; TYK2 Kinase; Tyrosine/metabolism

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Spermatozoa / Protein-Tyrosine Kinases / Signal Transduction / Proteins / Trans-Activators / DNA-Binding Proteins Limits: Humans / Male Language: En Journal: Fertil Steril Year: 2001 Document type: Article

Search on Google

XML

PubMed Links