Alteration of cardiac and renal functions in transgenic mice overexpressing human mineralocorticoid receptor.

Le Menuet, D; Isnard, R; Bichara, M; Viengchareun, S; Muffat-Joly, M; Walker, F; Zennaro, M C; Lombès, M

Le Menuet, D; Isnard, R; Bichara, M; Viengchareun, S; Muffat-Joly, M; Walker, F; Zennaro, M C; Lombès, M.

Affiliation

Le Menuet D; INSERM U478, Faculté de Médecine Xavier Bichat, 75018 Paris, Service de cardiologie, Institut Féderatif de Recherche 14, Centre hospitalier Universitaire Pitié-Salpetrière, 75013 Paris, France.

J Biol Chem ; 276(42): 38911-20, 2001 Oct 19.

Article in En | MEDLINE | ID: mdl-11495902

Subject(s)

Heart/physiology; Immediate-Early Proteins; Kidney/physiology; Mice, Transgenic; Nuclear Proteins; Receptors, Mineralocorticoid/biosynthesis; Animals; Blotting, Northern; DNA, Complementary/metabolism; DNA-Binding Proteins/biosynthesis; Early Growth Response Protein 1; Humans; Kidney/metabolism; Male; Mice; Models, Genetic; Myocardium/metabolism; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Protein Serine-Threonine Kinases/biosynthesis; Receptors, Mineralocorticoid/genetics; Recombinant Proteins/metabolism; Signal Transduction; Sodium-Potassium-Exchanging ATPase/biosynthesis; Time Factors; Tissue Distribution; Transcription Factors/biosynthesis

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Collection: 01-internacional Database: MEDLINE Main subject: Mice, Transgenic / Nuclear Proteins / Receptors, Mineralocorticoid / Immediate-Early Proteins / Heart / Kidney Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans / Male Language: En Journal: J Biol Chem Year: 2001 Document type: Article

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