Activated MEK1 binds the nuclear MyoD transcriptional complex to repress transactivation.

Perry, R L; Parker, M H; Rudnicki, M A

Perry, R L; Parker, M H; Rudnicki, M A.

Affiliation

Perry RL; Department of Biology, McMaster University, Hamilton, Ontario, Canada.

Mol Cell ; 8(2): 291-301, 2001 Aug.

Article in En | MEDLINE | ID: mdl-11545732

Subject(s)

MAP Kinase Signaling System/physiology; Mitogen-Activated Protein Kinase Kinases/metabolism; Muscle, Skeletal/physiology; MyoD Protein/metabolism; Protein Serine-Threonine Kinases/metabolism; Transcriptional Activation/genetics; Animals; Cell Differentiation/physiology; Cell Fractionation; Cells, Cultured; Fibroblasts/physiology; Genes, Reporter/genetics; Immunoblotting; MAP Kinase Kinase 1; Mice; Microscopy, Fluorescence; Muscle Development; Muscle, Skeletal/cytology; Muscle, Skeletal/growth & development; MyoD Protein/genetics; Nuclear Proteins/metabolism; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins/genetics; Recombinant Fusion Proteins/metabolism; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Transcriptional Activation / Protein Serine-Threonine Kinases / MyoD Protein / Muscle, Skeletal / Mitogen-Activated Protein Kinase Kinases / MAP Kinase Signaling System Limits: Animals Language: En Journal: Mol Cell Year: 2001 Document type: Article

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