Loss of heterozygosity on chromosome 13q12-q14, BRCA-2 mutations and lack of BRCA-2 promoter hypermethylation in sporadic epithelial ovarian tumors.

Gras, E; Cortes, J; Diez, O; Alonso, C; Matias-Guiu, X; Baiget, M; Prat, J

Gras, E; Cortes, J; Diez, O; Alonso, C; Matias-Guiu, X; Baiget, M; Prat, J.

Affiliation

Gras E; Department of Pathology, Hospital Santa Creu i Sant Pau, Autonomous University of Barcelona, 08025 Barcelona, Spain.

Cancer ; 92(4): 787-95, 2001 Aug 15.

Article in En | MEDLINE | ID: mdl-11550149

Subject(s)

Carcinoma/genetics; Chromosomes, Human, Pair 13; Loss of Heterozygosity; Mutation; Neoplasm Proteins/genetics; Ovarian Neoplasms/genetics; Transcription Factors/genetics; BRCA2 Protein; DNA Methylation; DNA, Neoplasm/analysis; Female; Genes, Tumor Suppressor; Humans; Microsatellite Repeats; Pedigree; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Sequence Analysis, DNA

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Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Transcription Factors / Chromosomes, Human, Pair 13 / Carcinoma / Loss of Heterozygosity / Mutation / Neoplasm Proteins Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Cancer Year: 2001 Document type: Article

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