Dendritic cells transduced with HSV-1 amplicons expressing prostate-specific antigen generate antitumor immunity in mice.

Willis, R A; Bowers, W J; Turner, M J; Fisher, T L; Abdul-Alim, C S; Howard, D F; Federoff, H J; Lord, E M; Frelinger, J G

Willis, R A; Bowers, W J; Turner, M J; Fisher, T L; Abdul-Alim, C S; Howard, D F; Federoff, H J; Lord, E M; Frelinger, J G.

Affiliation

Willis RA; Department of Microbiology and Immunology, University of Rochester, Rochester, NY 14642, USA.

Hum Gene Ther ; 12(15): 1867-79, 2001 Oct 10.

Article in En | MEDLINE | ID: mdl-11589829

Subject(s)

Cancer Vaccines; Dendritic Cells/cytology; Dendritic Cells/metabolism; Herpesvirus 1, Human/genetics; Immunotherapy/methods; Neoplasms/therapy; Prostate-Specific Antigen/biosynthesis; Animals; Antigen-Presenting Cells/metabolism; Cell Line; Chromium Radioisotopes/metabolism; Coculture Techniques; Epithelial Cells/metabolism; Flow Cytometry; Genetic Vectors; Green Fluorescent Proteins; Humans; Hybridomas; Luminescent Proteins/metabolism; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Plasmids/metabolism; Prostatic Neoplasms/metabolism; Time Factors; Transduction, Genetic

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Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Prostate-Specific Antigen / Herpesvirus 1, Human / Cancer Vaccines / Immunotherapy / Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Hum Gene Ther Year: 2001 Document type: Article

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