Effect of cross-tolerance between endotoxin and TNF-alpha or IL-1beta on cellular signaling and mediator production.

Ferlito, M; Romanenko, O G; Ashton, S; Squadrito, F; Halushka, P V; Cook, J A

Ferlito, M; Romanenko, O G; Ashton, S; Squadrito, F; Halushka, P V; Cook, J A.

Affiliation

Ferlito M; Department of Physiology and Neuroscience, Medical University of South Carolina, Charleston, USA.

J Leukoc Biol ; 70(5): 821-9, 2001 Nov.

Article in En | MEDLINE | ID: mdl-11698503

Subject(s)

Endotoxins/pharmacology; I-kappa B Proteins; Interleukin-1/pharmacology; MAP Kinase Signaling System/drug effects; Thromboxane B2/biosynthesis; Tumor Necrosis Factor-alpha/pharmacology; Culture Media, Conditioned; DNA-Binding Proteins/metabolism; Drug Interactions; Drug Tolerance; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Leukemic/drug effects; Interleukin-1 Receptor-Associated Kinases; JNK Mitogen-Activated Protein Kinases; Leukemia, Monocytic, Acute/pathology; Mitogen-Activated Protein Kinase 1/metabolism; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases/metabolism; Monocytes/drug effects; Monocytes/metabolism; NF-KappaB Inhibitor alpha; NF-kappa B/metabolism; Neoplasm Proteins/biosynthesis; Neoplasm Proteins/genetics; Phosphorylation/drug effects; Protein Kinases/metabolism; Protein Processing, Post-Translational/drug effects; Thromboxane B2/genetics; Tumor Cells, Cultured/drug effects; Tumor Cells, Cultured/metabolism; Tumor Necrosis Factor-alpha/biosynthesis; Tumor Necrosis Factor-alpha/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Thromboxane B2 / Interleukin-1 / Tumor Necrosis Factor-alpha / MAP Kinase Signaling System / I-kappa B Proteins / Endotoxins Language: En Journal: J Leukoc Biol Year: 2001 Document type: Article

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