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TT dinucleotides containing an isoxazoline moiety: synthesis and binding affinity study.
Kong, J R; Kim, S K; Moon, B J; Kim, S J; Kim, B H.
Affiliation
  • Kong JR; Department of Chemistry, Center for Integrated Molecular Systems, Pohang University of Science and Technology, Pohang, Korea.
Nucleosides Nucleotides Nucleic Acids ; 20(10-11): 1751-60, 2001.
Article in En | MEDLINE | ID: mdl-11719989
ABSTRACT
We have prepared four diastereomers of TT dinucleotides containing an isoxazoline moiety and four dodecanucleotides incorporating these TT dinucleotides in the middle of the DNA sequence. We also have determined the melting temperatures of these modified oligonucleotides (Tm values) by measuring change in UV absorbance.
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Collection: 01-internacional Database: MEDLINE Main subject: Isoxazoles / Nucleotides Language: En Journal: Nucleosides Nucleotides Nucleic Acids Year: 2001 Document type: Article
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PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Isoxazoles / Nucleotides Language: En Journal: Nucleosides Nucleotides Nucleic Acids Year: 2001 Document type: Article