Safety evaluation of phytosterol esters. Part 7. Assessment of mutagenic activity of phytosterols, phytosterol esters and the cholesterol derivative, 4-cholesten-3-one.

Wolfreys, A M; Hepburn, P A

Wolfreys, A M; Hepburn, P A.

Affiliation

Wolfreys AM; SEAC-Safety and Environmental Assurance Centre, Unilever Laboratory Colworth, Sharnbrook, MK44 1LQ, Bedford, UK. alison.wolfreys@unilever.com

Food Chem Toxicol ; 40(4): 461-70, 2002 Apr.

Article in En | MEDLINE | ID: mdl-11893405

Subject(s)

Cholestenones/adverse effects; Chromosome Aberrations/chemically induced; Phytosterols/adverse effects; Animals; Bone Marrow; DNA/biosynthesis; Escherichia coli/drug effects; Esters/adverse effects; Liver/pathology; Male; Micronucleus Tests; Mutagenicity Tests; Rats; Salmonella typhimurium/drug effects

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Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Phytosterols / Cholestenones / Chromosome Aberrations Limits: Animals Language: En Journal: Food Chem Toxicol Year: 2002 Document type: Article

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