Chlamydia pneumoniae in central retinal artery occlusion.
Acta Ophthalmol Scand
; 80(6): 656-9, 2002 Dec.
Article
in En
| MEDLINE
| ID: mdl-12485289
ABSTRACT
PURPOSE:
There is increasing evidence that the common respiratory human pathogen Chlamydia pneumoniae has a causative role in atherosclerosis. We investigated the association of this pathogen with acute central retinal artery occlusion (CRAO). PATIENTS ANDMETHODS:
Sera of 14 consecutive patients with CRAO and of 14 age- and sex-matched control subjects were examined. Antibodies against chlamydial lipopolysaccharide (LPS) and outer membrane proteins of C. pneumoniae were determined by an enzyme-linked immunosorbent assay (ELISA).RESULTS:
In the CRAO group, seven patients (50%) were found to be IgA positive, 12 (86%) were IgG positive and one (7%) was IgM positive for chlamydial LPS antibodies. In the control group 36%, 79% and 14% were IgA, IgG and IgM positive, respectively. The results showed no significant difference between the groups. In the CRAO group, IgA, IgG and IgM antibodies to C. pneumoniae were found in 43%, 79% and 0% of subjects, respectively. These findings did not differ significantly from those pertaining to matched controls.CONCLUSIONS:
These data do not support an association between acute CRAO and current C. pneumoniae infection.
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Collection:
01-internacional
Health context:
4_TD
Database:
MEDLINE
Main subject:
Retinal Artery Occlusion
/
Eye Infections, Bacterial
/
Chlamydophila pneumoniae
/
Pneumonia, Bacterial
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Acta Ophthalmol Scand
Year:
2002
Document type:
Article