Troglitazone-induced liver failure: a case study.

Graham, David J; Green, Lanh; Senior, John R; Nourjah, Parivash

Graham, David J; Green, Lanh; Senior, John R; Nourjah, Parivash.

Affiliation

Graham DJ; Office of Drug Safety, Center for Drug Evaluation and Research, Food and Drug Administration, 5600 Fishers Lane, HFD-400, Room 15B-32, Rockville, MD 20857, USA. grahamd@cder.fda.gov

Am J Med ; 114(4): 299-306, 2003 Mar.

Article in En | MEDLINE | ID: mdl-12681458

Subject(s)

Chemical and Drug Induced Liver Injury/etiology; Chromans/adverse effects; Liver Failure, Acute/chemically induced; Thiazoles/adverse effects; Thiazolidinediones; Age Distribution; Aged; Chemical and Drug Induced Liver Injury/epidemiology; Chromans/administration & dosage; Chronic Disease; Confidence Intervals; Diabetes Mellitus, Type 2/drug therapy; Dose-Response Relationship, Drug; Drug and Narcotic Control; Female; Humans; Liver Failure/chemically induced; Liver Failure/epidemiology; Liver Failure, Acute/epidemiology; Liver Function Tests; Male; Middle Aged; Odds Ratio; Probability; Registries; Risk Assessment; Severity of Illness Index; Sex Distribution; Survival Rate; Thiazoles/administration & dosage; Troglitazone; United States; United States Food and Drug Administration

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Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Chromans / Liver Failure, Acute / Thiazolidinediones / Chemical and Drug Induced Liver Injury Type of study: Etiology_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: America do norte Language: En Journal: Am J Med Year: 2003 Document type: Article

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