Synergistic effects of nimesulide and 5-fluorouracil on tumor growth and apoptosis in the implanted hepatoma in mice.

Li, Xiao-Hong; Li, Xiao-Kun; Cai, Shao-Hui; Tang, Fu-Xing; Zhong, Xue-Yun; Ren, Xian-Da

Li, Xiao-Hong; Li, Xiao-Kun; Cai, Shao-Hui; Tang, Fu-Xing; Zhong, Xue-Yun; Ren, Xian-Da.

Affiliation

Li XH; Department of Pharmacokinetics, Pharmacy College, Jinan University, Guangzhou 510632, Guangdong Province, China.

World J Gastroenterol ; 9(5): 936-40, 2003 May.

Article in En | MEDLINE | ID: mdl-12717833

Subject(s)

Fluorouracil/administration & dosage; Liver Neoplasms, Experimental/drug therapy; Liver Neoplasms, Experimental/pathology; Sulfonamides/administration & dosage; Animals; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage; Antimetabolites, Antineoplastic/administration & dosage; Apoptosis/drug effects; Cyclooxygenase Inhibitors/administration & dosage; Dinoprostone/metabolism; Drug Synergism; Liver Neoplasms, Experimental/metabolism; Mice; Microscopy, Electron; Proto-Oncogene Proteins c-fos/metabolism; Proto-Oncogene Proteins c-jun/metabolism; Tumor Suppressor Protein p53/metabolism

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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Sulfonamides / Fluorouracil / Liver Neoplasms, Experimental Limits: Animals Language: En Journal: World J Gastroenterol Year: 2003 Document type: Article

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